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    Papillary Carcinoma of Thyroglossal

    Duct Cyst

    Dr. Pawanjit Rohila

    Prof. R.K.Karwasra

    Deptt. Of Surgery and Surgical Oncology

    Pt. BD Sharma PGIMS Rohtak

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    Carcinomas of thyroglossal duct cysts are extremelyrare (1.5%)

    Papillary.80%

    Mixed papillary/follicular9.5%

    Squamous cell.7.6%

    Others.2.9%

    Most of the times the diagnosis is postoperative

    There is no clear consensus regarding furthermanagement after adequate excision of the cyst

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    40 years old female presented with asymptomatic ,submental,midline swelling for last 5 years, increasing in sizefor last 6 months and increased suddenly after FNAC

    6x6x4 cm non-tender, firm mass at the level of hyoid bone Not moving with deglutition and protrusion of tongue

    Bilaterally palpable cervical lymph nodes

    X-ray STN revealed soft tissue mass anterior to hyoid without

    calcifications Patient was euthyroid and thyroid gland was normally located

    on ultrasonography

    FNAC of the mass reported to be Adenomatous goiter

    Case One

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    Pre-op Diagnosis : Thyroglossal Duct cyst with hematoma following FNAC

    PLAN : Sistrunks procedure with frozen section examination

    Operative Findings6x6x5cm mass having blood clots within, adherent

    to hyoid and bilateral multiple nodes

    Thyroid was normal upon palpation

    Sistrunks procedure performed

    Tissue sent for Frozen Section Examination

    Papillary carcinoma in TGDC with invasion of cyst

    wall, LN

    +for metastasis

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    Total thyroidecectomy with bilateral MRND (type III) performed

    Final Histopathology Report Revealed

    Papillary Carcinoma in a thyroglossal duct cyst with extracystic extension

    Normal thyroid tissue in cyst wall, both lobes of Thyroid

    showing normal structure without any focus ofmalignancy

    Level II, III, and VI nodes positive for metastasis

    I131 SCAN..1.6% UPTAKE

    PATIENT REFERRED FOR RADIOABLATION

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    2nd Case 24 years old female presented with progressively increasing

    asymptomatic midline swelling in sub-mental region for last

    1 years and pain in the swelling for last 25 days after FNAC. 44 cms. Firm, non-tender mass above the level of hyoid

    bone .

    Moving with deglutition and protrusion of tongue without

    palpable cervical LAP. Patient was euthyroid and thyroid gland was normally located

    on USG.

    FNAC of the mass reported to be metastasis from papillarycarcinoma of thyroid.

    CECT neck revealed a hypo dense lesion of 4.54 cm withcalcification showing heterogeneous enhancement seen inthe floor of mouth. Few subcentimetric lymph nodes wereseen in bilateral cervical region.

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    Pre-op diagnosis : TGDC with Papillary carcinoma

    Plan : Sistrunks opn. With Total Thyroidectomy and LN Sampling

    Operative findings 4.54 cm Fibrocystic mass above the hyoid bone

    adherent to the underlying muscles

    Thyroid gland was normal on palpation

    A single enlarged level II lymph node on the right side. Few enlarged lymph nodes were excised

    Frozen section examination ofLNs revealed reactivehyperplasia

    Formal neck dissection not done.

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    Total thyroidectomy with Sistrunks operation performed

    Final Histopathology Report revealed

    Thyroid as unremarkable

    Lymph nodes as reactive.

    Papillary carcinoma in ectopic thyroid tissue

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    No Clear Consensus In LiteratureRegarding Management

    Sistrunks Procedure With Thyroid

    Suppression

    V/STotal Thyroidectomy With MND

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    Justifications For Total Thyroidectomy

    Any papillary carcinoma in neck originates in thyroidgland

    Papillary carcinomas are multifocal in origin

    Enables post operative thyroid scan and thyroidablation

    Thyroglobulin estimation is more relevant if there is

    no thyroidPatient needs thyroid suppression therefore why to

    leave the possible culprit behind ?

    Procedure is safe and has low morbidity

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    Our view

    Total thyroidectomy is safe with lowmorbidity

    Patient follow-up and management is bettercontrolled after thyroidectomy

    Radio ablation is possible only afterthyroidectomy

    Patient takes Eltroxin lifelong in either case so

    why to leave the possible culprit behind?

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    Thanks