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    Full Year 2015 Results

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    Forward looking statements

    This document may contain forward-looking statements that may or may not prove accurate. For example,statements regarding expected revenue growth and trading margins, market trends and our product pipeline areforward-looking statements. Phrases such as "aim", "plan", "intend", "anticipate", "well-placed", "believe","estimate", "expect", "target", "consider" and similar expressions are generally intended to identify forward-lookingstatements. Forward-looking statements involve known and unknown risks, uncertainties and other importantfactors that could cause actual results to differ materially from what is expressed or implied by the statements. ForSmith & Nephew, these factors include: economic and financial conditions in the markets we serve, especiallythose affecting health care providers, payers and customers; price levels for established and innovative medicaldevices; developments in medical technology; regulatory approvals, reimbursement decisions or other governmentactions; product defects or recalls or other problems with quality management systems or failure to comply withrelated regulations; litigation relating to patent or other claims; legal compliance risks and related investigative,remedial or enforcement actions; disruption to our supply chain or operations or those of our suppliers; competitionfor qualified personnel; strategic actions, including acquisitions and dispositions, our success in performing duediligence, valuing and integrating acquired businesses; disruption that may result from transactions or other

    changes we make in our business plans or organisation to adapt to market developments; and numerous othermatters that affect us or our markets, including those of a political, economic, business, competitive or reputationalnature. Please refer to the documents that Smith & Nephew has filed with the U.S. Securities and ExchangeCommission under the U.S. Securities Exchange Act of 1934, as amended, including Smith & Nephew's mostrecent annual report on Form 20-F, for a discussion of certain of these factors. Any forward-looking statement isbased on information available to Smith & Nephew as of the date of the statement. All written or oral forward-looking statements attributable to Smith & Nephew are qualified by this caution. Smith & Nephew does notundertake any obligation to update or revise any forward-looking statement to reflect any change in circumstances

    or in Smith & Nephew's expectations. 2

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    Chief Executive OfficerOlivier Bohuon

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    Full year 2015 highlights

    Key Comments

    Revenues +4% underlying (+0%reported)

    Advanced Wound Care +8%

    Recon +3% with Knees +5% Sports Medicine Joint Repair +7% Emerging Markets +11%

    Five technology and distributionacquisitions

    Trading profit margin 23.7% (+80bps) EPSA 85.1 (+2% reported, +9% CER)

    Full year dividend 30.8 (up 4%)

    Full Year

    2015 2014Underlying

    growth

    $m $m %

    Revenue 4,634 4,617 4

    Trading profit 1,099 1,055 5

    Trading Profit Margin 23.7% 22.9%

    EPSA 85.1 83.2

    4

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    Progress on our Strategic Priorities in 2015

    5

    ShareholderVa

    lue

    Strong existing product portfolio and new models Attractive pipeline, both internal and acquired Creating single R&D function to focus pipeline development

    Strong double digit growth ex China Acquisitions in Russia, Colombia, mid-tier

    Emerging markets growth story remains intact

    Emerging Markets

    Established Markets Strong US dynamic (AWM turn-around, Recon, Sports Med) Europe stabilised Increased focus on commercial excellence

    Innovation

    Group optimisation plan delivering on benefits

    Extending single MD model to US Establishing Global Business ServicesSimplification

    Acquisitions Success of Arthrocare and Healthpoint acquisitions Emerging market deals strengthening position Attractive technologies - ZUK, Blue Belt Technologies

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    Driving commercial excellence and pioneering

    innovation

    6

    Commercial

    Regional salesorganisations

    Globalcommercialorganisation

    GlobalR&D

    GlobalOperations

    Customer-facingfranchises

    Businesssupport

    functions

    Single MD model in allEstablished and

    Emerging countries

    Commercial strategyUpstream marketing

    Market accessSalesforce excellence

    Pricing

    FinanceHR

    LegalCompliance

    IT

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    Pioneering innovative technologies and models

    7

    SportsMedicine

    Leading knee , hipand shoulder

    portfolios COBLATION &

    DYONICS

    Rotator CuffSolution

    WEREWOLF

    Regenerative e.g.BST-CarGel

    Segment-leadinggrowth

    Hip & Knee

    VERILASTtechnology

    JOURNEYII family ZUK uni knee

    Syncera model NAVIO system

    REDAPT revisionhip

    Segment-leadinggrowth

    Wound

    ALLEVYN Life PICO

    SANTYL

    RENASYS TOUCH Solutions based

    models

    Segment-leadinggrowth

    TODAY:

    Drive growth withdifferentiated products

    FUTURE:Accelerate growth withdisruptive innovations

    and solutions

    Note: excludes mid-tier, ENT, GYN and Trauma & Extremities portfolios

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    Three full years since acquisition

    Provided scale to our US woundmanagement business

    Transaction delivered results aheadof plan

    3-year sales CAGR >20%

    Year three ROCE exceeds WACC

    Building a strong M&A track record

    8

    First full year since acquisition

    Integration completed

    Results tracking to plan Cost synergies achieved

    US Sports Medicine benefiting fromsales synergies

    Enterprise Value: $0.8bn Enterprise Value: $1.5bn

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    2%

    9%

    0% 5% 10% 15%

    Excluding ChinaEmerging

    Est OUS

    US

    AWD

    AWB

    AWC

    Hips

    Knees

    ArthroscopicEnabling Tech

    Sports MedicineJoint Repair

    Trauma &Extremities

    Other Surgical

    15%

    16%

    4%

    1%

    6%

    13%

    0%

    3%

    9%

    0% 10% 20%

    Q4 revenue growth of 5% underlying

    9

    Geographical growth Product franchise growthRevenue split

    Underlying change (%) Underlying change (%)

    Note: Est OUS is Australia, Canada, Europe, Japan and New Zealand, Other Surgical includes Gynaecology and ENT.

    14%2%

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    Sports Medicine, Trauma & OSB

    Q4 Revenue performance Sports Medicine Joint Repair +9% ($169m)

    Arthroscopic Enabling Technologies (AET) +3% ($159m)

    Trauma & Extremities +0% ($127m)

    Other Surgical Businesses* +13% ($56m)

    Commentary

    both Joint Repair and AET benefitting from ArthroCareintegration

    very strong US Joint Repair growth (+17%) led by shoulder

    ENT and GYN generating good growth

    10* Other Surgical Businesses includes Gynaecology and ENT

    Comprehensive ProductOfferings for Rotator Cuff Repair

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    Q4 Revenue performance

    Knees: global +6%*, US +7%*, OUS +4%* ($248m)

    Hips: global +1%, US +0%, OUS +1% ($163m)

    Commentary continued strong growth in global Knees

    ZUK sales ahead of guidance

    Blue Belt Technologies acquisition completed andintegration off to a good start

    Reconstruction

    11* Excludes the effect of ZUK product acquisition

    JOURNEYII BCSBi-Cruciate StabilisedKnee System

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    Advanced Wound Management

    Q4 Revenue performance Advanced Wound Care +4% ($196m)

    Advanced Wound Bioactives +16% ($96m)

    Advanced Wound Devices +14% ($43m)

    Commentary sustainable improvement in AWC trend

    AWB strong final quarter as expected

    AWD benefitted from PICO growth

    12

    PICOSingle Use Negative Pressure Wound

    Therapy

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    Chief Financial OfficerJulie Brown

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    14

    Growth

    2015 2014 Reported CER(1) Underlying(2)

    Revenue $4,634m $4,617m 0% 8% 4%

    Trading Profit $1,099m $1,055m 4% 10% 5%

    Trading Margin 23.7% 22.9%

    EPSA 85.1 83.2 2% 9%

    Trading cash flow $936m $781m

    Free cash flow $672m $308m

    Full Year Financial Highlights

    (1)Constant exchange rates(2)Growth at constant exchange rates, adjusted for acquisitions and disposals

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    FY 2015(1)Q4 2015(1)

    Q4 and Full Year Revenue growth

    15(1)

    Q4 2015 comprises 64 trading days (2014 63 trading days). Full year comprises 251 days (2014 251 days)(2)Constant exchange rates

    Growth % Growth %

    Underlying Underlying

    Acquisitions Acquisitions

    CER(2) CER(2)

    Currency Currency

    Reported Reported

    5%

    2%

    7%

    -6%

    1%

    4%

    4%

    8%

    -8%

    0%

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    16

    Full Year

    2015 2014

    $m $m

    Revenue 4,634 4,617

    Cost of goods sold (1,143) (1,127)

    Gross profit 3,491 3,490

    Gross profit margin 75.3% 75.6%

    Selling, general and admin (2,170) (2,200)

    Research and development (222) (235)

    Trading profit 1,099 1,055

    Trading profit margin 23.7% 22.9%

    Full year trading income statement

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    17

    Group trading margin 2015

    Trading margin history Selected 2015 margin drivers

    2013 2014 2015

    22.7%22.9%

    23.7% Group optimisation

    ArthroCare synergies

    Price, mix and exchange

    RENASYShold

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    18

    Full year IFRS profit adjusting itemsFull Year

    2015 2014

    $m $m

    Trading profit 1,099 1,055

    Acquisition related costs (12) (118)

    Restructuring and rationalisation (65) (61)

    Amortisation of acquisition intangibles (204) (129)

    Legal and other items (190) 2

    IFRS Operating profit 628 749

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    19

    Metal on metal

    Majority of US metal-on-metal hip claims settled

    Insurance covered majority of settlement

    $25m net cash cost (incl. insurance receivable to date)

    Q4 accounting charge of $203m

    Represents cost of US settlement, net of insurance, and presentvalue of all other current and anticipated claims, before insurance

    Excludes future legal charges

    Group carries considerable product liability insurance

    Legal settlements

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    Full Year Growth

    2015 2014 Reported CER

    $m $m

    Trading profit 1,099 1,055 4% 10%

    Interest receivable 6 13

    Interest payable (47) (28)

    Other finance costs (13) (11)

    Share of results from associate (5) (2)

    Adjusted profit before tax 1,040 1,027

    Taxation (279) (284) Tax rate* 26.8%

    Adjusted attributable profit 761 743

    Number of shares million 894 893

    Adjusted earnings per share ("EPSA") 85.1 83.2 2% 9%

    Earnings per share ("EPS") 45.9 56.1

    20

    Full year EPSA and EPS

    * Full year rate on Trading results

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    Full year free cash flow

    21

    Full Year2015 2014

    $m $m

    Trading profit 1,099 1,055

    Share based payment 29 32

    Depreciation and amortisation 307 310Capital expenditure (358) (375)

    Movements in working capital (141) (241)

    Trading cash flow 936 781

    Trading cash conversion 85% 74%

    Restructuring, rationalisation, acquisition & other (91) (195)

    Operating cashflow after capital expenditure 845 586

    Net interest paid (36) (33)

    Taxation paid (137) (245)

    Free cash flow 672 308

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    (1,613)(1,361)

    1,030

    -

    (358)

    (272) (71) (77)

    (1,800)

    (1,600)

    (1,400)

    (1,200)(1,000)

    (800)

    (600)

    (400)

    (200)

    0

    Dec-14Net Debt

    FCF precapex

    Capex Dividends Acquisitions Share buyback

    Other Dec-15Net Debt

    Cash flow and capital allocation

    22

    $m

    Reinvest fororganicgrowth

    Progressivedividendpolicy

    Acquisitionin line withstrategy

    Returnexcess toshare-holders1 2 3 4

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    EPSA growth at CER

    Trading margin development

    EstablishedMarkets

    Revenue growth

    23

    Emerging

    Markets

    Innovation

    Simplification

    Acquisitions

    OptimisingCash

    Deliveringreturnsthrough

    capitalallocationframework

    Our 2016 guidance

    Maintain good underlying growth

    Continued tax rate improvement

    Continued margin improvement;

    more than offset by FX and Blue Belt

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    Chief Executive OfficerOlivier Bohuon

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    Summary

    2015 delivered acceleration in sales and improvement in profitability

    sustained improvement in franchises and regions

    strong execution of efficiency programmes

    further strengthening through acquisitions

    Outlook

    continue the positive underlying revenue growth trend

    in the medium term, we anticipate increasingly outperforming our markets

    strategy continues to transform the profile of Smith & Nephew

    25

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    Questions

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    Appendices

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    2016 Technical guidance

    28

    Guidance Full year

    Restructuring costs c. $50m

    Acquisition and integration costs c. $10m

    Amortisation of acquisition intangibles c. $140m

    Income from associates Slightly negative

    Interest payable(1) ~ 3%

    Other finance costs c. $10m

    Tax rate on Trading result 26.5% or slightly lower

    (1)Long term borrowings were $1,434m at the end of 2015, pre Blue Belt.

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    29

    H1 H2 Full Year

    2015 2014 2015 2014 2015 2014

    $m $m $m $m $m $m

    Revenue 2,272 2,220 2,362 2,397 4,634 4,617

    Cost of goods sold (566) (538) (577) (589) (1,143) (1,127)

    Gross profit 1,706 1,682 1,785 1,808 3,491 3,490

    Gross profit margin 75.1% 75.8% 75.6% 75.4% 75.3% 75.6%

    Selling, general and admin (1,084) (1,078) (1,086) (1,122) (2,170) (2,200)

    Research and development (110) (120) (112) (115) (222) (235)

    Trading profit 512 484 587 571 1,099 1,055

    Trading profit margin 22.5% 21.8% 24.9% 23.8% 23.7% 22.9%

    Trading income statement - half and full year

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    30

    IFRS profit adjusting items half and full year

    H1 H2 Full Year

    2015 2014 2015 2014 2015 2014

    $m $m $m $m $m $m

    Trading profit 512 484 587 571 1,099 1,055

    Acquisition related costs (13) (58) 1 (60) (12) (118)

    Restructuring and rationalisation (19) (19) (46) (42) (65) (61)

    Amortisation of acquisition intangibles (78) (54) (126) (75) (204) (129)

    Legal and other items 37 10 (227) (8) (190) 2

    IFRS Operating profit 439 363 189 386 628 749

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    H1 H2 Full Year2015 2014 2015 2014 2015 2014

    $m $m $m $m $m $m

    Trading profit 512 484 587 571 1,099 1,055

    Interest receivable 2 7 4 6 6 13

    Interest payable (23) (11) (24) (17) (47) (28)

    Other finance costs (7) (5) (5) (6) (13) (11)

    Share of results from associate (3) (2) (2) - (5) (2)

    Adjusted profit before tax 481 473 559 554 1,040 1,027

    Taxation (131) (133) (148) (151) (279) (284)

    Adjusted attributable profit 350 340 411 403 761 743

    Number of shares million 894 893 894 893 894 893

    Adjusted earnings per share ("EPSA") 39.1 38.1 46.0 45.1 85.1 83.2

    Earnings per share ("EPS") 33.0 26.8 12.9 29.3 45.9 56.131

    EPSA and EPS half and full year

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    Free cash flow half and full year

    32

    H1 H2 Full Year

    2015 2014 2015 2014 2015 2014

    $m $m $m $m $m $m

    Trading profit 512 484 587 571 1,099 1,055

    Share based payment 13 16 16 16 29 32

    Depreciation and amortisation 148 140 159 170 307 310

    Capital expenditure (161) (161) (197) (214) (358) (375)

    Movements in working capital (130) (222) (11) (19) (141) (241)

    Trading cash flow 382 257 554 524 936 781

    Trading cash conversion 75% 53% 94% 92% 85% 74%

    Restructuring, rationalisation,acquisition & other

    36 (37) (127) (158) (91) (195)

    Operating cash flow 418 220 427 366 845 586

    Net interest paid (17) (12) (19) (21) (36) (33)

    Taxation paid (72) (136) (65) (109) (137) (245)

    Free cash flow 329 72 343 236 672 308

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    Franchise revenue analysis

    33All revenue growth rates are on an underlying basis* Other Surgical Businesses includes Gynaecology and ENT

    2014 2015

    Q1 Q2 Q3 Q4 FullYear

    Q1 Q2 Q3 Q4 Full year

    Growth Growth Growth Growth Growth Growth Growth Growth Growth Revenue Growth

    % % % % % % % % % $m %

    Sports Medicine, Trauma &OSB

    2 6 7 5 5 5 4 2 5 1,881 4

    Sports Medicine Joint Repair 5 9 11 8 8 9 7 4 9 606 7

    Arthroscopic EnablingTechnologies (2) (1) 3 2 1 (2) 1 (2) 3 573 -

    Trauma & Extremities (1) 7 8 3 4 5 2 2 - 497 2

    Other Surgical Businesses* 23 18 6 6 10 11 7 10 13 205 10

    Reconstruction - 3 1 2 2 1 4 3 4 1,487 3

    Knee Implants - 2 1 3 2 2 7 6 6 883 5

    Hip Implants - 3 1 2 1 (1) 1 (2) 1 604 -

    Advanced Wound Management - - (1) (2) (1) 1 7 6 8 1,266 6

    Advanced Wound Care (6) (8) (3) (1) (4) 9 12 6 4 755 8

    Advanced Wound Bioactives 8 21 14 16 15 5 6 2 16 344 7

    Advanced Wound Devices 13 1 (17) (27) (9) (27) (9) 17 14 167 (3)

    Group 1 3 3 2 2 3 5 4 5 4,634 4

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    Regional revenue analysis

    34

    Other Established Markets is Australia, Canada, Europe, Japan and New Zealand.All revenue growth rates are on an underlying basis

    2014 2015Q1 Q2 Q3 Q4

    FullYear

    Q1 Q2 Q3 Q4 Full year

    Growth Growth Growth Growth Growth Growth Growth Growth Growth Revenue Growth

    % % % % % % % % % $m %

    Geographic regions

    US (2) 4 2 - 1 1 4 4 9 2,217 5

    Other Established Markets 1 (3) (2) (1) (1) (2) 3 1 2 1,702 1

    Established Markets (1) 1 - - - - 3 3 6 3,919 3

    Emerging Markets 9 17 20 18 17 22 14 8 2 715 11

    Group 1 3 3 2 2 3 5 4 5 4,634 4

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    Analysis of restructuring costs

    35

    Of the $57m total charged in the full year, all $57m are reflected in selling, general and administrative expenses and nothing incost of goods sold in the Group Income Statement.

    Structural Efficiency target of $160m cash costs and $40m asset write-offs.

    Group Optimisation target of $150m total costs.

    P&L Charge Cash Spend

    PreviousTotal to Date

    FY Total to datePrevious

    Total to DateFY Total to date

    Group OptimisationPlan

    $m $m $m $m $m $m

    Cash costs 48 57 105 39 45 84

    Asset w/offs - - - n/a n/a n/a

    Total 48 57 105 39 45 84

    Structural EfficiencyProgramme

    $m $m $m $m $m $m

    Cash costs 141 8 149 139 7 146

    Asset w/offs 21 - 21 n/a n/a n/a

    Total 162 8 170 139 7 146

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    Business days per quarter

    36

    Q1 Q2 Q3 Q4 Full Year

    2014 62 63 63 63 251

    2015 61 63 63 64 251

    2016 64 64 63 60 251

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    Exchange rates

    37

    Q4/14 FY/14 Q1/15 Q2/15 Q3/15Q4/1

    5FY/15

    $:

    Period end 1.21 1.21 1.09 1.12 1.12 1.09 1.09Average 1.25 1.33 1.13 1.11 1.11 1.10 1.11

    $:

    Period end 1.56 1.56 1.49 1.57 1.52 1.48 1.48

    Average 1.58 1.65 1.51 1.53 1.55 1.52 1.53

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