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DENOMINACION DEL GRUPO Neurofarmacología

GRUPOS DE INVESTIGACION EN BIOMEDICINA Y CIENCIAS DE LA SALUDPágina 1 de 26

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TIPO DE INVESTIGACION:AREA TEMATICA:

ENTIDADES PARTICIPANTES:

063

Neurología y sentidos Básica orientada

Universidad de Castilla-La Mancha (UCLM)

Fecha de actualizacion de los datos: 10/02/2015

Investigadores actuales del grupo

Nota: La información sobre los grupos es proporcionada por los investigadores principales de los mismos y se actualiza de forma permanente. El grupo da su consentimiento para que aparezca o no una determinada información sobre el mismo. Cualquier grupo puede solicitar su inclusión en el portal.

, (Investigador principal) Facultad de Medicina de AlbaceteJordán Bueso, Joaquín (Investigador principal) Facultad de Medicina de AlbaceteCano Cuenca, NievesProy vega, Beatriz

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Proyectos financiados.

Año Financiación Entidad financiadora / tituloExpediente

09055-00 2009 Ministerio de Ciencia e Innovación0,00Implicacion de la cinasa ATM y las proteínas BH3 en un modelo experimental de Parkinson asociado al envejecimiento

PI-2007/55 2008 FISCAM. JCCM155.543,10Estudio de los mecanismos celulares implicados en la alteración de la permeabilidad de la

07031-00 2007 Ministerio de Sanidad y Consumo91.300,00Papel de la mitocondria en las rutas apoptóticas activadas durante la neurotoxicidad

2005 Infraestructura FEDER (MCYT). Ministerio de Educación y Ciencia78.325,54Laboratorio de Bioseguridad P2

2005 Infraestructura FEDER (MCYT). Ministerio de Educación y Ciencia281.738,14Equipamiento científico para el animalario de la Facultad de Medicina de la UCLM

2005 Infraestructura FEDER (MCYT). Ministerio de Educación y Ciencia87.158,10Instalaciones de gases especiales

04005-00 2005 Consejería de Sanidad. JCCM178.710,00Mecanismos celulares y moleculares como posibles dianas farmacológicas en un modelo

04095-00 2005 Ministerio de Sanidad y Consumo. FIS110.000,00 Precondicionamiento farmacológico: mecanismos de neuroprotección frente al daño producido por la toxina mitocondrial malonato

04096-00 2004 Universidad de Castilla-La Mancha0,00p53 en los procesos neurodegenerativos

03081-00 2003 Consejería de Ciencia y Tecnología de JCCM90.000,00Regulación de p53 en los procesos de muerte neuronal como diana farmacológica.

1FD97-0500 1999 CICYT324.942,00Nuevas dianas terapéuticas en neuroprotección: canales iónicos y mecanismos antioxidantes

SAF99-0060 1999 CICYT84.150,0012/03/2015Impreso:




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Papel del poro de transición de permeabilidad mitocondrial en la muerte neuronal...

Resumen de proyectos financiados por cualquier agencia.

Año FinanciaciónNº

1999 409.092,002

2003 90.000,001

2004 0,001

2005 735.931,785

2007 91.300,001

2008 155.543,101

2009 0,001

1.481.866,8812Total

Resumen de artículos publicados

Artículos en el ISI-JCR

Número

F.I. medio*

Percentil medio F.I.

Artículos no ISI-JCR Número

Totales 5 últimos añosAnteriores a los 5

últimos años

99 50

6 2

49

8

3,49

64,34

Numero medio de citas ** 14,19

3,50 3,48

65,10 63,57

3,89 26,88

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Total de artículos Número 56 51107

* Factor de impacto actualizado al último ISI-JCR disponible** Número de citas recibidas actualizado a 15/02/2015. Solo disponible para los artículos en los que consta un centro de trabajo radicado en Castilla-La Mancha

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Resumen de artículos

Artículos en ISI-JCR

Número F.I.* medio

Percentil medio

Artículos no ISI-JCR Total de articulos

Número Número

* Factor de impacto actualizado al último ISI-JCR disponible

Número medio citas**

** Número de citas recibidas actualizado a 15/02/2015. Solo disponible para los artículos en los que consta un centro de trabajo radicado en Castilla-La Mancha

2 0 22015 1,52 52,50 0,00

5 1 62014 4,52 73,40 0,83

10 2 122013 3,88 72,40 2,83

7 2 92012 3,72 67,29 2,89

6 1 72011 2,28 49,17 1,29

20 0 202010 3,54 64,65 7,76

10 1 112009 3,58 68,20 12,38

13 0 132008 3,55 64,62 22,18

4 1 52007 3,25 66,25 28,60

2 0 22006 4,34 72,00 26,00

6 0 62005 3,98 68,67 22,00

6 0 62004 2,88 51,17 40,60

6 0 62003 3,29 59,67 50,17

1 0 12002 5,07 92,00 30,00

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1 0 12000 0,77 15,00 0,00

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Relación de artículos

Nº Citas F.I. Percentil

* Factor de impacto actualizado al último ISI-JCR disponible

** Número de citas recibidas actualizado a 15/02/2015. Solo disponible para los artículos en los que consta un centro de trabajo radicado en Castilla-La Mancha

Título Autores Referencias Centros participantes

Automatic quantification of the subcellular localization of chimeric GFP protein supported by a two-level Naive Bayes classifier

2015 851,85Saez-Atienzar, S; Martinez-Gomez, J;Alonso-Barba, JI; Puerta, JM;Galindo, MF; Jordan, J; de la Ossa, L

[Saez-Atienzar, Sara; Jordan, Joaquin] Univ Castilla LaMancha, IDINE, Fac Med Albacete, Dept Ciencias Med,Grp Neurofarmacol, E-13071 Ciudad Real, Spain; [Martinez-Gomez, Jesus; Alonso-Barba, Juan Ignacio; Puerta, Jose Miguel; de la Ossa, Luis] I3A Univ Castilla La Mancha, Dept Sistemas Informat, Grp Invest SistemasInteligentes & Mineria Datos, E-13071 Ciudad Real, Spain;[Galindo, Maria F.] Univ Castilla La Mancha, Complejo Hosp Univ Albacete, Fac Farm, Area Tecnol Fannaceut,UnidadNeuropsicofarmacol T, E-13071 Ciudad Real, Spain

0Expert Systems with Applications 42 ():1531-1537

[Latrepirdine: a systematic review of the preclinicalstudies]

2015 201,18Cano-Cuenca N;Solis-Garcia DelPJ;Jordan J;

Universidad de Castilla La Mancha. Facultad de Medicina, 02006 Albacete, Espana

0Rev Neurol 60 ():35-42

Evidence for the Efficacy of Latrepirdine (Dimebon)Treatment for Improvement of Cognitive Function: AMeta-Analysis

2014 754,17Cano-Cuenca, N; Pozoc, JESG;Jordan, J

[Cano-Cuenca, Nieves; Jordan, Joaquin] Univ Castilla La Mancha, Fac Med Albacete, Dept Ciencias Med, Albacete02008, Spain; [Cano-Cuenca, Nieves] Complejo Hosp Albacete, Serv Farm, Albacete, Spain; [Solis-Garcia del Pozoc, Julian E.] Hosp Gen Villarrobledo, Serv Med Interna, Albacete, Spain; [Jordan, Joaquin] Inst Invest Discapacidades Neurol UCL, Grp Neurofarmacol, Albacete, Spain

5J ALZHEIMERS DIS 38 (1):155-164

Anxiolytic-like effects and mechanism of (-)-myrtenol:A monoterpene alcohol

2014 302,03Moreira, MRC; Salvadori, MGDS; deAlmeida, AAC; de Sousa, DP;Jordan, J; Satyal, P; de Freitas, RM; de Almeida, RN

[Candido Moreira, Maria Rosilene; de Almeida, ReinaldoNobrega] Univ Fed Paraiba, Postgrad Program BiotechnolPgRENORBIO, BR-58059900 Joao Pessoa, Paraiba, Brazil; [Candido Moreira, Maria Rosilene; Cardoso de Almeida, Antonia Amanda; de Freitas, Rivelilson Mendes] Univ FedPiaui, Lab Res Expt Neurochem LAPNEX, Teresina, PI, Brazil; [da Silva Stiebbe Salvadori, Mirian Graciela; deAlmeida, Reinaldo Nobrega] Univ Fed Paraiba, Postgrad Program Nat Prod & Bioact Synthet PgPNSB, BR-58059900 Joao Pessoa, Paraiba, Brazil; [de Sousa, Damiao Pergentino]Univ Fed Paraiba, Dept Pharmaceut Sci, BR-58059900 Joao Pessoa, Paraiba, Brazil; [Jordan, Joaquin] Univ Castilla La Mancha, Dept Med Sci, E-13071 Ciudad Real, Spain; [Satyal,Prabodh] Univ Alabama Huntsville, Dept Chem, Huntsville, AL 35816 USA

0NEUROSCI LETT 579 ():119-124

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Autophagy and mitochondrial alterations in human retinal pigment epithelial cells induced by ethanol:implications of 4-hydroxy-nonenal

2014 816,04Flores-Bellver, M; Bonet-Ponce, L;Barcia, JM; Garcia-Verdugo, JM;Martinez-Gil, N; Saez-Atienzar, S;Sancho-Pelluz, J; Jordan, J; Galindo,MF; Romero, FJ

[Flores-Bellver, M.; Bonet-Ponce, L.; Barcia, J. M.;Martinez-Gil, N.; Saez-Atienzar, S.; Sancho-Pelluz, J.; Romero, F. J.] Catholic Univ Valencia, Sch Med & Dent, DeptPhysiol, Valencia, Spain; [Garcia-Verdugo, J. M.] Univ Valencia, Dept Comparat Neurobiol, Cavanilles Inst Biodivers & Evolut Biol, Valencia, Spain; [Jordan, J.] Univ Castilla La Mancha, IDINE, Sch Med, Neuropharmacol Grp,Dept Med Sci, Albacete, Spain; [Galindo, M. F.] Univ Castilla La Mancha, Unit Translat Neuropsychopharmacol, Albacete,Spain; [Galindo, M. F.] Albacete Hosp, Albacete, Spain

0CELL DEATH DIS 5 ():0-0

[Are scientific literature databases a good source of scientific evidence for discontinuing a drug from themarket?]

2014 Proy-Vega B;Cano-CuencaN;Solis-Garcia Del PJ;Jordan J;

Grupo de Neurofarmacologia. IDINE-Universidad Castilla-LaMancha. Servicio de Farmacia. Hospital de Hellin. [email protected] de Neurofarmacologia.IDINE-Universidad Castilla-La Mancha. Servicio de MedicinaInterna. Hospital de Villarrobledo. [email protected] de Neurofarmacologia.IDINE-Universidad Castilla-La Mancha.Servicio de Farmacia.Complejo Hospitalario Universitario de [email protected] de Neurofarmacologia.IDINE-Universidad Castilla-La Mancha. Ciencias Medicas. Facultad de Medicina. Universidad Castilla-La Mancha.. [email protected]

0Farm Hosp 38 ():381-382

Sildenafil Decreases BACE1 and Cathepsin B Levelsand Reduces APP Amyloidogenic Processing in the SAMP8 Mouse

2014 1004,31Orejana L;Barros-Minones L;JordanJ;Cedazo-Minguez A;TorderaRM;Aguirre N;Puerta E;

Department of Pharmacology, School of Pharmacy, University of Navarra, SpainDepartment of Pharmacology, School ofPharmacy, University of Navarra, SpainDepartment of Medical Sciences, School of Medicine, University of Castilla-LaMancha and Regional Centre for Biomedical Research, Albacete, SpainDepartment of Neurobiology, Care Sciencesand Society, Karolinska Institutet-Alzheimer Disease Research Center, Stockholm, SwedenDepartment ofPharmacology, School of Pharmacy, University of Navarra, SpainDepartment of Pharmacology, School of Pharmacy, University of Navarra, SpainDepartment of Pharmacology, School of Pharmacy, University of Navarra, Spain. Department of Neurobiology, Care Sciences and Society,Karolinska Institutet-Alzheimer Disease Research Center,Stockholm, Sweden

0

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The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission andmitochondrial-derived ROS signaling

2014 816,04Saez-Atienzar, S; Bonet-Ponce, L;Blesa, JR; Romero, FJ; Murphy, MP;Jordan, J; Galindo, MF

[Saez-Atienzar, S.; Jordan, J.] Univ Castilla La Mancha, Fac Med Albacete, Dept Ciencias Med, Grp Neurofarmacol,IDINE, Albacete, Spain; [Saez-Atienzar, S.;Bonet-Ponce, L.; Blesa, J. R.; Romero, F. J.] Univ Catolica Valencia San Vicente Martir Valenci, Fac Med & Odontol, Valencia, Spain; [Saez-Atienzar, S.; Galindo, M. F.] ComplejoHosp Univ Albacete, Unidad Neuropsicofarmacol Traslac,Albacete 02006, Spain; [Murphy, M. P.] Wellcome Trust Res Labs, Mitochondrial Biol Unit, Cambridge, England

0CELL DEATH DIS 5 ():0-0

Minocycline mediated mitochondrial cytoprotection:premises for therapy of cerebrovascular andneurodegenerative diseases

2013 823,85Karachitos, A; del Pozo, JSG; deGroot, PWJ; Kmita, H; Jordan, J

[Karachitos, Andonis; Kmita, Hanna] Adam Mickiewicz Univ, Lab Bioenerget, Inst Mol Biol & Biotechnol, Fac Biol,PL-61614 Poznan, Poland; [Garcia del Pozo, Julian Solis] Hosp Villarrobledo, Med Interna Serv, Albacete 02600, Spain; [de Groot, Piet W. J.] Univ Castilla La Mancha, Reg CtrBiomed Res, Albacete 02006, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Dpto Ciencias Med, Fac Med Albacete, IDINE, Albacete 02006, Spain

4Curr Drug Targets 14 ():47-55

Confocal microscopy for astrocyte in vivo imaging:recycle and reuse in microscopy

2013 794,47Perez-Alvarez, A; Araque, A; Martin,ED

[Perez-Alvarez, Alberto; Araque, Alfonso] CSIC, Inst Cajal, E-28002 Madrid, Spain; [Martin, Eduardo D.] Univ Castilla La Mancha, Inst Invest Discapacidades Neurol, Albacete, Spain

3FRONT CELL NEUROSCI 7 ():0-0

Inhibition of calpain-regulated p35/cdk5 plays a centralrole in sildenafil-induced protection against chemical hypoxia produced by malonate

2013 864,91Barros-Minones, L;Martin-de-Saavedra, D;Perez-Alvarez, S; Orejana, L; Suquia,V; Goni-Allo, B; Hervias, I; Lopez,MG; Jordan, J; Aguirre, N; Puerta, E

[Barros-Minones, Lucia; Orejana, Lourdes; Suquia, Veronica; Goni-Allo, Beatriz; Hervias, Isabel; Aguirre, Norberto; Puerta,Elena] Univ Navarra, Sch Pharm, Dept Pharmacol, Pamplona 31008, Spain; [Perez-Alvarez, Sergio; Jordan, Joaquin] Univ Castilla La Mancha, Sch Med, Dept Med Sci, GrpNeuropharmacol, Albacete, Spain; [Perez-Alvarez, Sergio;Jordan, Joaquin] Inst Invest Discapacidades Neurol IDINE,Albacete, Spain; [Martin-de-Saavedra, Dolores; Lopez, Manuela G.] Univ Autonoma Madrid, Inst Teofilo Hernando,E-28049 Madrid, Spain

4BBA-MOL BASIS DIS 1832 (6):705-717

Latrepirdine is a potent activator of AMP-activated protein kinase and reduces neuronal excitability

2013 Weisova, P; Alvarez, SP; Kilbride,SM; Anilkumar, U; Baumann, B;Jordan, J; Bernas, T; Huber, HJ;Dussmann, H; Prehn, JHM

[Weisova, P.; Alvarez, S. P.; Kilbride, S. M.; Anilkumar, U.; Baumann, B.; Bernas, T.; Huber, H. J.; Duessmann, H.; Prehn, J. H. M.] Royal Coll Surgeons Ireland, Dept Physiol &Med Phys, Ctr Study Neurol Disorders, Dublin 2, Ireland;[Weisova, P.] Univ Vienna, Max F Perutz Labs, Vienna,Austria; [Alvarez, S. P.; Jordan, J.] Univ Castilla La Mancha, Fac Med, Dpto Ciencias Med Farmacol, Albacete, Spain; [Bernas, T.] Inst Expt Biol PAS, Warsaw, Poland

1TRANSL PSYCHIAT 3 ():0-0

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MINOCYCLINE BLOCKS ALLERGEN-INDUCEDEOSINOPHILIA AND PRODUCTION OF TH2 CYTOKINES AND IGE BY INTERFERING WITHTHE T CELLRECEPTOR-NF-kB-GATA-3-INTERLEUKIN (IL)-4AXIS IN A MURINE ASTHMA MODEL WITHOUTAN EFFECT ON PARP

2013 935,70Naura, AS; Kim, H; Ju, JH;Rodriguez, PC; Jordan, J; Pyakurel,K; Tarhuni, AF; Ochoa, AC;Boulares, HA

[Naura, Amarjit S.; Kim, Hogyoung; Ju, Jihang; Rodriguez, Paulo C.; Pyakurel, Kusma; Tarhuni, Abdelmetalab F.;Ochoa, Augusto C.; Boulares, Hamid A.] LSU Hlth Sci Ctr,Stanley Scot Canc Ctr, New Orleans, LA USA; [Jordan, Joaquin] UCLM, Albacete, Spain

0FASEB J 27 ():0-0

Minocycline Blocks Asthma-associated Inflammationin Part by Interfering with the T Cell Receptor-Nuclear Factor kappa B-GATA-3-IL-4 Axis without a Prominent Effect on Poly(ADP-ribose) Polymerase

2013 794,65Naura, AS; Kim, H; Ju, JH;Rodriguez, PC; Jordan, J; Catling,AD; Rezk, BM; Abd Elmageed, ZY; Pyakurel, K; Tarhuni, AF;Abughazleh, MQ; Errami, Y; Zerfaoui,M; Ochoa, AC; Boulares, AH

[Naura, Amarjit S.; Kim, Hogyoung; Ju, Jihang; Rodriguez, Paulo C.; Catling, Andrew D.; Abd Elmageed, Zakaria Y.; Pyakurel, Kusma; Tarhuni, Abdelmetalab F.; Abughazleh,Mohammad Q.; Errami, Youssef; Zerfaoui, Mourad; Ochoa, Augusto C.; Boulares, A. Hamid] Louisiana State Univ, Hlth Sci Ctr, Stanley S Scott Canc Ctr, New Orleans, LA 70112 USA; [Kim, Hogyoung; Ju, Jihang; Catling, Andrew D.; Pyakurel, Kusma; Tarhuni, Abdelmetalab F.; Errami, Youssef; Zerfaoui, Mourad; Boulares, A. Hamid] Louisiana State Univ, Hlth Sci Ctr, Dept Pharmacol & Expt Therapeut, NewOrleans, LA 70112 USA; [Naura, Amarjit S.] Louisiana State Univ, Hlth Sci Ctr, Dept Med, New Orleans, LA 70112 USA; [Jordan, Joaquin] Univ Castilla La Mancha, Dpto CienciasMed, Fac Med, Albacete 02006, Spain; [Rezk, Bashir M.] So Univ New Orleans, Dept Nat Sci, New Orleans, LA 70126 USA

3J BIOL CHEM 288 (3):1458-1468

Requiem for tetrazepam2013 201,18Proy-Vega, B; Cano-Cuenca, N;Aguirre, C; del Pozo, JSG; Jordan, J

[Proy-Vega, Beatriz; Cano-Cuenca, Nieves] Complejo HospUniv Albacete, Serv Farm, Albacete, Spain; [Proy-Vega, Beatriz; Cano-Cuenca, Nieves; Solis-Garcia del Pozo, Julian; Jordan, Joaquin] Univ Castilla La Mancha, IDINE, Grp Neurofarmacol, E-02006 Albacete, Spain; [Aguirre, Carmelo] Univ Basque Country, Fac Med, Dept Farmacol, Albacete, Spain; [Aguirre, Carmelo] Hosp Galdakao Usansolo, Unidad Farmacovigilancia Comunidad Autonoma Vasca, Albacete,Spain; [Solis-Garcia del Pozo, Julian] Hosp Gen Villarrobledo,Med Interna Serv, Albacete, Spain; [Jordan, Joaquin] UnivCastilla La Mancha, Fac Med Albacete, Dept Ciencias Med, E-02006 Albacete, Spain

0REV NEURO LOGIA 57 (1):1-2

3-Nitropropionic acid induces autophagy by forming mitochondrial permeability transition pores rather than activatiing the mitochondrial fission pathway

2013 925,07Solesio, ME; Saez-Atienzar, S;Jordan, J; Galindo, MF

[Solesio, Maria E.; Galindo, Maria F.] Univ Albacete, ComplejoHosp, Unidad Neuropsicofarmacol Traslac, Albacete 02006, Spain; [Saez-Atienzar, Sara; Jordan, Joaquin] Univ Castilla LaMancha, Fac Med Albacete, Dpto Ciencias Med, Grp Neurofarmacol,IDINE, Albacete, Spain

6BRIT J PHARMACOL 168 (1):63-75

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Advances in the understanding of retinal drug disposition and the role of blood-ocular barrier transporters

2013 702,94Jordan, J; Ruiz-Moreno, JM [Jordan, Joaquin] Castilla La Mancha Univ, Grp Neuropharmacol, Albacete, Spain; [Ruiz-Moreno, Jose M.] Castilla La Mancha Univ, Dept Ophthalmol, Albacete, Spain; [Ruiz-Moreno, Jose M.] Castilla La Mancha Univ, Fac Med Albacete, Dept Ciencias Med, Albacete 02006, Spain

0EXPERT OPIN DRUG MET 9 (9):1181-1192

Rasagiline in Parkinson's disease: A review based on meta-analysis of clinical data

2013 864,35Minguez-Minguez, S; del Pozo, JSG;Jordan, J

[Minguez-Minguez, Sara; Jordan, Joaquin] Univ Castilla La Mancha, Fac Med Albacete, Dept Ciencias Med, E-13071 Ciudad Real, Spain; [Solis-Garcia del Pozo, Julian] Hosp Gen Villarrobledo, Med Interna Serv, Villarrobledo 02600, Albacete, Spain; [Jordan, Joaquin] Univ Castilla La Mancha,Inst Invest Discapacidades Neurol, Grp Neurofarmacol,E-13071 Ciudad Real, Spain

5PHARMACOL RES 74 ():78-86

The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease

2013 Solesio, ME; Prime, TA; Logan, A;Murphy, MP; Arroyo-Jimenez, MD;Jordan, J; Galindo, MF

[Solesio, Maria E.; Galindo, Maria F.] Complejo Hosp Univ Albacete, Unidad Neurofarmacol Traslac, Albacete 02006, Spain; [Prime, Tracy A.; Logan, Angela; Murphy, Michael P.] MRC, Mitochondrial Biol Unit, Cambridge CB2 0XY, England;[del Mar Arroyo-Jimenez, Maria] Univ Castilla La Mancha,CRIB, Dpto Ciencias Med, Grp Neuroanat Humana, Albacete, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, IDINE, FacMed Albacete, Grp Neurofarmacol,Dpto Ciencias Med,Albacete, Spain

8BBA-MOL BASIS DIS 1832 (1):174-182

The senescence-accelerated mouse prone-8(SAM-P8) oxidative stress is associated with upregulation of renal NADPH oxidase system

2013 371,65Baltanas, A; Solesio, ME; Zalba, G; Galindo, MF; Fortuno, A; Jordan, J

[Baltanas, Ana; Zalba, Guillermo; Fortuno, Ana] Univ Navarra, Ctr Appl Med Res, Div Cardiovasc Sci, Pamplona 31008,Spain; [Solesio, Maria E.; Galindo, Maria F.] Albacete Univ Hosp Ctr, Translat Neuropsychopharmacol Unit, Albacete, Spain; [Zalba, Guillermo] Univ Navarra, Dept Biochem & Genet, Pamplona 31008, Spain; [Galindo, Maria F.] Univ Castilla La Mancha, Dept Med Sci, Albacete, Spain; [Jordan,Joaquin] Univ Castilla La Mancha, Sch Med, Dept Med Sci,Albacete 02006, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Neuropharmacol Grp, Albacete, Spain

0J PHYSIOL BIOCHEM 69 (4):927-935

Characterization of Mitophagy in the 6-Hydoxydopamine Parkinson's Disease Model

2012 924,33Solesio, ME; Saez-Atienzar, S;Jordan, J; Galindo, MF

[Saez-Atienzar, Sara; Jordan, Joaquin] Univ Castilla LaMancha, Fac Med Albacete, Dpto Ciencias Med, Grp Neurofarmacol,IDINE, Albacete, Spain; [Solesio, Maria E.;Galindo, Maria F.] Complejo Hosp Univ Albacete, Unidad Neuropsicofarmacol Traslac, Albacete, Spain

9TOXICOL SCI 129 (2):411-420

Cytoprotective activity of minocycline includesimprovement of mitochondrial coupling: the importance of minocycline concentration and the presence of VDAC

2012 251,60Karachitos, A; Jordan, J; Kmita, H [Karachitos, Andonis; Kmita, Hanna] Adam Mickiewicz Univ, Fac Biol, Inst Mol Biol & Biotechnol, Lab Bioenerget,PL-61614 Poznan, Poland; [Jordan, Joaquin] Univ Castilla La Mancha, Albacete Coll Med, Dept Med Sci, Neuropharmacol Grp, Albacete, Spain

1J BIOENERG BIOMEMBR 44 (3):297-307

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Is huntingtin a modulator of VDAC?2012 854,62Karachitos, A; Stobienia, O; Jordan,J; De Pinto, V; Kmita, H

[Karachitos, A.; Stobienia, O.; Kmita, H.] Adam MickiewiczUniv, Fac Biol, Inst Mol Biol & Biotechnol, Lab Bioenerget, Poznan, Poland; [Jordan, J.] Univ Castilla La Mancha, Dept Med Sci, Neuropharmacol Grp, Albacete, Spain; [De Pinto,Vito] Univ Catania, Mol Biol Sect, Dept Biol Geol & EnvironmSci, I-95124 Catania, Italy; [De Pinto, Vito] Natl Inst Biomembranes & Biosyst, Sect Catania, I-95125 Catania, Italy

0BBA-BIOENERGETICS 1817 ():S121-S121

Long-Lasting Neuroprotective Effect of SildenafilAgainst 3,4-Methylenedioxymethamphetamine-induced5-Hydroxytryptamine Deficits in the Rat Brain

2012 532,97Puerta, E; Barros-Minones, L;Hervias, I; Gomez-Rodriguez, V;Orejana, L; Pizarro, N; de la Torre, R; Jordan, J; Aguirre, N

[Puerta, Elena; Barros-Minones, Lucia; Gomez-Rodriguez, Violeta; Orejana, Lourdes; Aguirre, Norberto] Univ Navarra, Dept Pharmacol, Sch Pharm, Pamplona 31008, Spain; [Hervias, Isabel] Univ Navarra, CIMA, Div Neurosci, Pamplona 31008, Spain; [de la Torre, Rafael] IMIM, Pharmacol Res Unit, Barcelona, Spain; [de la Torre, Rafael]Univ Pompeu Fabra, Barcelona, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Sch Med, Dept Med Sci, Albacete, Spain; [Jordan, Joaquin] Reg Ctr Biomed Res, Albacete, Spain

3J NEUROSCI RES 90 (2):518-528

Minocycline exerts uncoupling and inhibiting effects on mitochondrial respiration through adenine nucleotide translocase inhibition

2012 864,35Cuenca-Lopez, MD; Karachitos, A;Massarotto, L; Oliveira, PJ; Aguirre,N; Galindo, MF; Kmita, H; Jordan, J

[Karachitos, Andonis; Kmita, Hanna] Adam Mickiewicz Univ, Fac Biol, Inst Mol Biol & Biotechnol, Lab Bioenerget,PL-61614 Poznan, Poland; [Jordan, Joaquin] Univ Castilla La Mancha, Fac Med Albacete, Dept Ciencias Med, Albacete02006, Spain; [Cuenca-Lopez, Maria D.; Jordan, Joaquin] IDINE UCLM, Grp Neurofarmacol, Albacete, Spain; [Massarotto, Luca] Univ Padua, Erasmus Program, I-35100Padua, Italy; [Massarotto, Luca; Oliveira, Paulo J.] Univ Coimbra, Ctr Neurosci & Cell Biol, P-3000 Coimbra, Portugal; [Aguirre, Norberto] Univ Navarra, Dept Farmacol, E-31080 Pamplona, Spain; [Galindo, Maria F.] CHUA, Unidad Neuropsicofarmacol Trasnac, Albacete, Spain

7PHARMACOL RES 65 (1):120-128

Modulation of apoptosis in acute ischemic stroke astreatment challenges

2012 Jordan J., Moreno-Parrado L.,Anton-Martinez D., Jellinger K.A.,Galindo M.F.

Grupo de Neurofarmacología, Dpto Ciencias Médicas, Fac de Medicina, Universidad de Castilla La Mancha, Avenida Almansa, 14, Albacete 02006, Spain; Sección de Microbiologia, Complejo Hospitalario Universitario de Albacete, Albacete, Spain; Sección de Bioquímica, ComplejoHospitalario Universitario de Albacete, Albacete, Spain; Institute of Clinical Neurobiology, Kenyongasse 18, A-1070 Vienna, Austria; Unidad de NeuropsicofarmacologíaTranslacional, Complejo Hospitalario Universitario de Albacete, c/ Hermanos Falcó 37, 02003 Albacete, Spain

0Current Immunology Reviews 8 ():39-49

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Pharmacological Characterization of the MechanismsInvolved in Delayed Calcium Deregulation in SH-SY5Y Cells Challenged with Methadone

2012 Perez-Alvarez S;SolesioME;Cuenca-Lopez MD;Melero-Fernandez de MeraRM;Villalobos C;Kmita H;GalindoMF;Jordan J;

Neuropharmacology, Department of Medical Sciences,School of Medicine, University of Castilla-La Mancha (UCLM), 02006 Albacete, Spain

0Int J Cell Biol 2012 ():642482-0

Anticonvulsant effect of phytol in a pilocarpine model in mice

2012 302,03Costa, JP; Ferreira, PB; De Sousa,DP; Jordan, J; Freitas, RM

[Costa, J. P.; Ferreira, P. B.; Freitas, R. M.] Univ Fed Piaui, Programa Posgrad Ciencias Farmaceut, Lab Res Expt Neurochem, BR-64049550 Teresina, Piaui, Brazil; [Costa, J. P.; De Sousa, D. P.] Univ Fed Sergipe, Dept Pharm,BR-49100000 Sao Cristovao, Sergipe, Brazil; [Jordan, J.] Univ Castlilla La Mancha, Dept Med Sci, Med Sch Albacete, Albacete 02006, Spain

6NEUROSCI LETT 523 (2):115-118

Sildenafil ameliorates cognitive deficits and tau pathology in a senescence-accelerated mouse model

2012 1006,17Orejana, L; Barros-Minones, L;Jordan, J; Puerta, E; Aguirre, N

[Orejana, Lourdes; Barros-Minones, Lucia; Puerta, Elena; Aguirre, Norberto] Univ Navarra, Dept Pharmacol, Sch Pharm, Pamplona 31008, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Sch Med, Dept Med Sci, Albacete, Spain; [Jordan, Joaquin] Reg Ctr Biomed Res, Albacete, Spain

0NEUROBIOL AGING 33 (3):0-0

Mitochondria: The Headquarters in Ischemia-InducedNeuronal Death

2011 Jordan J;de Groot PW;Galindo MF; Grupo de Neurofarmacologia, Dpto Ciencias Medicas,Facultad de Medicina, Universidad de Castilla-La Mancha, and Unidad de Neuropsicofarmacologia Translacional, Complejo Hospitalario Universitario de Albacete, C/Almansa, 14, 02006 Albacete. Spain. [email protected]

0

INFLAMMATION AND FRAILTY INDEX IN OLDERADULTS

2011 873,01Varo, G; Romero, C; Gonzalez, ML;Abizanda, P; Galindo, MF; Jordan, J

[Varo, G.; Romero, C.; Gonzalez, M. L.] Univ Hosp Albacete, Dept Clin Anal, Albacete, Spain; [Abizanda, P.] Univ Hosp Albacete, Dept Med Gerontol, Albacete, Spain; [Galindo, M.F.; Jordan, J.] Univ Castilla La Mancha, DeptNeuropharmacol, Fac Med, Albacete, Spain

0CLIN CHEM LAB MED 49 ():S196-S196

Lipoic acid alters amino acid neurotransmitters content in rat hippocampus after pilocarpine-induced seizures

2011 411,99de Freitas, RM; Silva, FD; Saldanha,GB; Jordan, J

[de Freitas, Rivelilson Mendes] Univ Fed Piaui, Lab Expt ResBiol Sci, Piaui, Brazil; [Silva, Fabio de Oliveira] Univ Fed Ceara, Dept Chem Organ & Inorgan, Fortaleza, Ceara, Brazil; [Saldanha, Glaucio Barros] Clin Pathol Lab, Fortaleza, Ceara,Brazil; [Jordan, Joaquin] Univ Castilla La Mancha, Fac Med,Grp Neuropharmacol, Dept Med Sci, Albacete, Spain; [Jordan, Joaquin] Ctr Reg Invest Biomed, Albacete, Spain

1FUND CLIN PHARMACO L 25 (4):485-492

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Methadone induces CAD degradation and AIF-mediated necrotic-like cell death in neuroblastomacells

2011 864,35Perez-Alvarez, S; Iglesias-Guimarais,V; Solesio, ME; de Mera, RMMF;Yuste, VJ; Galindo, MF; Jordan, J

[Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete 02006, Spain; [Iglesias-Guimarais, Victoria; Yuste, Victor J.] Univ Autonoma Barcelona, Fac Med, Dept Bioquim & Biol Mol, Inst Neurociencies, Bellaterra 08193, Spain; [Solesio, Maria E.; Galindo, Maria F.] Albacete Univ Hosp Ctr, TranslatNeuropsychopharmacol Unit, Albacete, Spain; [Jordan, Joaquin] IDINE UCLM, Grp Neurofarmacol, Albacete, Spain


Neuropharmacological effects of lipoic acid andubiquinone on delta-aminolevulinic dehydratase, Naplus , K plus -ATPase, and Mg2+-ATPase activities in rat hippocampus after pilocarpine-induced seizures

2011 411,99de Freitas, RM; Feng, DJ; Jordan, J [de Freitas, Rivelilson Mendes] Univ Fed Piaui, Lab Physiol & Pharmacol, BR-64600000 Picos, Piaui, Brazil; [Feng, Dejiang] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA; [Jordan, Joaquin] UCLM Ctr Reg Invest Biomed, Fac Med, Grp Neurofarmacol, Albacete, Spain

1FUND CLIN PHARMACO L 25 (2):211-216

Pharmacological targets in multiple sclerosis2011 201,18Varo-Sanchez, GM; Cuenca-Lopez,MD; Fernandez-Fernandez, O;Jordan, J

[Jordan, Joaquin] Univ Castilla La Mancha, Fac MedAlbacete, Dept Ciencias Med, E-02006 Albacete, Spain; [Fernandez-Fernandez, Oscar] Hosp Reg Univ Carlos Haya, Inst Neurociencias Clin, Malaga, Spain; [Varo-Sanchez, Gema M.] Complejo Hosp Univ Albacete, Serv Anal Clin,Malaga, Spain; [Varo-Sanchez, Gema M.; Dolores Cuenca-Lopez, M.] IDINE UCLM, Grp Neurofarmacol,Malaga, Spain


The role played by toll-like receptors in cerebral infarction processes

2011 201,18Jordan, J [Jordan, Joaquin] Univ Castilla La Mancha, IDINE, Grp Neurofarmacol, E-02006 Albacete, Spain; [Jordan, Joaquin]Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, E-02006 Albacete, Spain


Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells

2010 894,58Garcia-Martinez, EM; Sanz-Blasco, S;Karachitos, A; Bandez, MJ;Fernandez-Gomez, FJ;Perez-Alvarez, S; de Mera, RMMF;Jordan, MJ; Aguirre, N; Galindo, MF;Villalobos, C; Navarro, A; Kmita, H;Jordan, J

[Jordan, Joaquin] Univ Castilla La Mancha, Ctr Reg Invest Biomed, Grp Neurofarmacol, Dept Ciencias Med,Fac Med, Albacete 02006, Spain; [Maria Garcia-Martinez, Eva]Complejo Hosp Univ Albacete, Serv Farm Hosp, Albacete, Spain; [Sanz-Blasco, Sara; Villalobos, Carlos] Univ Valladolid, CSIC, IBGM, Valladolid, Spain; [Karachitos, Andonis; Kmita,Hanna] Adam Mickiewicz Univ Poznan, Fac Biol, Inst Mol Biol& Biotechnol, Lab Bioenerget, PL-61614 Poznan, Poland;[Bandez, Manuel J.; Navarro, Ana] Univ Cadiz, Fac Med, Cadiz, Spain; [Jordan, Maria J.] Inst Murciano Invest & Desarrollo Agr & Alimentar, Murcia, Spain; [Aguirre, Norberto]Univ Navarra, Fac Med, E-31080 Pamplona, Spain; [Galindo,Maria F.] Complejo Hosp Univ Albacete, Unidad Pfizer Castilla La Mancha Neuropsicofarmac, Albacete, Spain

39BIOCHEM PHARMACO L 79 (2):239-250

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Lipoic acid blocks seizures induced by pilocarpine via increases in delta-aminolevulinic dehydratase and Na+, K+-ATPase activity in rat brain

2010 602,61Santos, IMD; Tome, AD; Feitosa, CM;de Souza, GF; Feng, DJ; de Freitas, RM; Jordan, J

[de Sales Santos, Itala Monica; Feitosa, Chistiane Mendes; de Freitas, Rivelilson Mendes] Univ Fed Piaui, Lab Expt Res Biol Sci, Teresina, Piaui, Brazil; [Tome, Adriana da Rocha] Univ Estadual Ceara, Fortaleza, Ceara, Brazil; [de Souza, GeaneFelix] Clin Pathol Lab, Fortaleza, Ceara, Brazil; [Feng, Dejiang] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA; [Jordan, Joaquin] Univ Castilla La Mancha, Grp Neuropharmacol, Dept Med Sci, Fac Med, Albacete, Spain; [Jordan, Joaquin] Ctr Reg Invest Biomed,Albacete, Spain

7PHARMACOL BIOCHEM BEHAV 95 (1):88-91

Neurochemical changes on oxidative stress in rathippocampus during acute phase of pilocarpine-induced seizures

2010 602,61de Freitas, RM; do Nascimento, KG;Ferreira, PMP; Jordan, J

[de Freitas, Rivelilson Mendes; Pinheiro Ferreira, Paulo Michel] Univ Fed Piaui, Lab Physiol & Pharmacol, BR-64600000 Picos, Piaui, Brazil; [do Nascimento, Katia Gomes] Univ Fed Ceara, Dept Physiol & Pharmacol, BR-60430270 Fortaleza, Ceara, Brazil; [Jordan, Joaquin] UnivCastilla La Mancha, Fac Med, Grp Neuropharmacol, DeptMed Sci, Albacete, Spain

4PHARMACOL BIOCHEM BEHAV 94 (3):341-345

ATM is involved in cell-cycle control through the regulation of retinoblastoma protein phosphorylation

2010 573,06Pizarro JG;Folch J;de la TorreAV;Junyent F;Verdaguer E;JordanJ;Pallas M;Camins A;

Unitat de Farmacologia i Farmacognosia, Institut de Biomedicina (IBUB), Centro deInvestigacion Biomedica en Red de Enfermedades Neurodegenerativas (CIBERNED), Facultat de Farmacia, Universitat de Barcelona, Nucli Universitari de Pedralbes, Barcelona E-08028, Spain

n.d.J Cell Biochem 110 ():210-218

Sildenafil protects against 3-nitropropionic acidneurotoxicity through the modulation of calpain, CREB,and BDNF

2010 875,62Puerta E;Hervias I;Barros-MinonesL;Jordan J;RicobarazaA;Cuadrado-Tejedor M;Garcia-OstaA;Aguirre N;

Department of Pharmacology, School of Medicine, University of Navarra, Pamplona, Spain

n.d.Neurobiol Dis 38 ():237-245

Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells

2010 864,35Pizarro JG;Junyent F;VerdaguerE;Jordan J;Beas-Zarate C;PallasM;Camins A;Folch J;

Unitat de Farmacologia i Farmacognosia, Institut de Biomedicina (IBUB), Centro de Investigacion Biomedica en Red de Enfermedades Neurodegenerativas (CIBERNED), Universitat de Barcelona, Nucli Universitari de Pedralbes, 08028 Barcelona, Spain

n.d.Pharmacol Res 61 ():391-399

Cholinesterase Activity in Brain of Senescence-Accelerated-Resistant Mouse SAMR1and Its Variation in Brain of Senescence-Accelerated-Prone Mouse SAMP8

2010 532,97Fernandez-Gomez, FJ;Munoz-Delgado, E; Montenegro, MF;Campoy, FJ; Vidal, CJ; Jordan, J

[Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, E-02006 Albacete, Spain; [Jose Fernandez-Gomez, Francisco; Munoz-Delgado,Encarnacin; Fernanda Montenegro, Maria; Campoy, Francisco J.; Vidal, Cecilio J.] Univ Murcia, Dept Bioquim &Biol Mol A, Murcia, Spain

7J NEUROSCI RES 88 (1):155-166

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Mitochondrial biology in Alzheimer's diseasepathogenesis

2010 723,97Galindo, MF; Ikuta, I; Zhu, XW;Casadesus, G; Jordan, J

[Jordan, Joaquin] Univ Castilla La Mancha, Grp Neurofarmacol, Ctr Reg Invest Biomed, Albacete 02006, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Dept Ciencias Med, Fac Med, Albacete 02006, Spain; [Galindo, Maria F.] Complejo Hosp Univ Albacete, Unidad Neuropsicofarmacol Translac, Albacete, Spain; [Ikuta, Ichiro] SUNY Upstate Med Univ, Coll Med, Syracuse, NY USA; [Zhu, Xiongwei] Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA; [Casadesus, Gemma] Case Western Reserve Univ, Dept Neurosci, Cleveland, OH 44106 USA

24J NEUROCHEM 114 (4):933-945

Delayed pre-conditioning by 3-nitropropionic acid prevents 3,4-methylenedioxymetamphetamine-induced5-HT deficits

2010 723,97Puerta, E; Pastor, F; Dvoracek, J; de Saavedra, MDM; Goni-Allo, B;Jordan, J; Hervias, I; Aguirre, N

[Puerta, Elena; Pastor, Fiona; Dvoracek, Jan; de Saavedra, Maria D. M.; Goni-Allo, Beatriz; Hervias, Isabel; Aguirre, Norberto] Univ Navarra, Dept Pharmacol, Sch Med,Pamplona 31008, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Reg Ctr Biomed Res, Sch Med, Dept Med Sci,Grp Neuropharmacol, Albacete, Spain

1J NEUROCHEM 114 (3):843-852

Inflammation as a therapeutic agent in cerebral infarction: cellular inflammatory response andinflammatory mediators

2010 201,18Cuenca-Lopez, MD; Brea, D; Segura,T; Galindo, MF; Anton-Martinez, D;Agulla, J; Castillo, J; Jordan, J

[Cuenca-Lopez, Maria D.; Jordan, Joaquin] Univ Castilla LaMancha, Dept Ciencias Med, Fac Med, E-02006 Albacete, Spain; [Brea, David; Agulla, Jesus; Castillo, Jose] Univ Santiago de Compostela, Hosp Clin Univ, Lab Invest Neurociencias Clin, Serv Neurol, Santiago De Compostela, Spain; [Anton-Martinez, David] Complejo Hosp Univ Albacete, Secc Bioquim, Albacete, Spain; [Jordan, Joaquin] Inst Invest Discapacidades Neurol Albacete, Grp Neurofarmacol,Albacete, Spain


Inflammatory response during ischaemic processes:adhesion molecules and immunomodulation

2010 201,18Cuenca-Lopez, MD; Brea, D; Galindo,MF; Anton-Martinez, D; Sanz, MJ;Agulla, J; Castillo, J; Jordan, J

[Brea, David; Agulla, Jesus; Castillo, Jose] Univ Santiago deCompostela, Lab Invest Neurociencias Clin, Serv Neurol,Hosp Clin Univ, Albacete, Spain; [Sanz, Maria J.] UnivValencia, Fac Med, Dept Farmacol, Albacete, Spain;[Cuenca-Lopez, Maria D.; Anton-Martinez, David; Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, E-02006 Albacete, Spain; [Galindo, Maria F.] ComplejoHosp Univ Albacete, Unidad Translac Neuropsicofamarcol, Albacete, Spain; [Anton-Martinez, David] Complejo Hosp Univ Albacete, Secc Bioquim, Albacete, Spain; [Jordan, Joaquin] Ctr Reg Invest Biomed, Grp Neurofarmacol, Albacete, Spain; [Jordan, Joaquin] Inst Invest Discapacidades NeurolAlbacete, Grp Neurofarmacol, Albacete, Spain


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Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures

2010 302,03Freitas, RM; Jordan, J; Feng, D [Freitas, R. M.] Univ Fed Piaui, Lab Physiol & Pharmacol,BR-64600000 Picos, Piaui, Brazil; [Jordan, J.] Univ CastillaLa Mancha, Fac Med, Dept Med Sci, Grp Neuropharmacol,Albacete, Spain; [Feng, D.] Univ Colorado, Dept Mol Cellular & Dev Biol, Boulder, CO 80309 USA

1NEUROSCI LETT 477 (3):129-133

Methadone induces necrotic-like cell death in SH-SY5Y cells by an impairment of mitochondrial ATP synthesis

2010 864,91Perez-Alvarez, S; Cuenca-Lopez, MD;de Mera, RMMF; Puerta, E;Karachitos, A; Bednarczyk, P; Kmita,H; Aguirre, N; Galindo, MF; Jordan, J

[Jordan, Joaquin] Univ Castilla La Mancha, Grp Neurofarmacol, Dept Ciencias Med, Fac Med,Coll Med, Albacete 02006, Spain; [Puerta, Elena; Aguirre, Norberto] Univ Navarra, Dept Pharmacol, Coll Med, E-31080 Pamplona, Spain; [Karachitos, Andonis; Kmita, Hanna] Adam Mickiewicz Univ Poznan, Fac Biol, Lab Bioenerget, Inst Mol Biol & Biotechnol, PL-61614 Poznan, Poland; [Bednarczyk, Piotr] Warsaw Univ Life Sci SGGW, Dept Biophys, PL-02776 Warsaw, Poland; [Galindo, Maria F.] Albacete Univ Hosp Ctr, Translat Neuropsychopharmacol Unit, Albacete, Spain;[Jordan, Joaquin] UCLM, Inst Neurol Disabil Res, Albacete, Spain

7BBA-MOL BASIS DIS 1802 (11):1036-1047

Methylenedioxymethamphetamine inhibitsmitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity

2010 925,07Puerta, E; Hervias, I; Goni-Allo, B;Zhang, SF; Jordan, J; Starkov, AA; Aguirre, N

[Puerta, Elena; Hervias, Isabel; Goni-Allo, Beatriz; Aguirre,Norberto] Univ Navarra, Dept Pharmacol, Sch Med,Pamplona 31008, Spain; [Zhang, Steven F.; Starkov, Anatoly A.] Cornell Univ, Dept Neurol & Neurosci, Weill Med Coll,New York, NY 10021 USA; [Jordan, Joaquin] Univ Castilla LaMancha, Dept Med Sci, Sch Med, Albacete, Spain; [Jordan,Joaquin] Reg Ctr Biomed Res, Albacete, Spain


ATM Is Involved in Cell-Cycle Control Through theRegulation of Retinoblastoma Protein Phosphorylation

2010 573,06Pizarro, JG; Folch, J; de la Torre, AV; Junyent, F; Verdaguer, E; Jordan, J; Pallas, M; Camins, A

[Pizarro, Javier G.; Vazquez de la Torre, Aurelio; Junyent, Felix; Verdaguer, Ester; Pallas, Merce; Camins, Antoni] Univ Barcelona, Fac Farm, Unitat Farmacol & Farmacognosia, Inst Biomed IBUB,Nucli Univ Pedralbes,CIBERNED, E-08028 Barcelona, Spain; [Folch, Jaume; Junyent, Felix] Univ Rovira & Virgili, Ctr Invest Biomed Red EnfermedadesNeurodegenerat, Fac Med & Ciencies Salut, Unitat Bioquim, E-43201 Reus, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Dept Ciencias Med, Fac Med, E-02006 Albacete, Spain

2J CELL BIOCHEM 110 (1):210-218

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Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease

2010 855,62Camins, A; Pizarro, JG; Alvira, D; Gutierrez-Cuesta, J; de la Torre, AV; Folch, J; Sureda, FX; Verdaguer, E;Junyent, F; Jordan, J; Ferrer, I;Pallas, M

[Camins, Antoni; Pizarro, Javier G.; Alvira, Daniel; Gutierrez-Cuesta, Javier; de la Torre, Aurelio Vazquez;Verdaguer, Ester; Junyent, Felix; Pallas, Merce] Univ Barcelona, Unitat Farmacol & Farmacog, Fac Farm, Inst Biomed IBUB,CIBERNED,Nuc li Univ Pedralbes, E-08028 Barcelona, Spain; [Folch, Jaume; Sureda, Francesc X.; Junyent, Felix] Univ Rovira & Virgili, Unitat Bioquim, CIBERNED, Fac Med & Ciencies Salut, E-43201 Reus, Tarragona, Spain; [Jordan, Joaquin] Univ Castilla La Mancha,Grp Neurofarmacol, Dept Ciencias Med, Fac Med, Albacete, Spain; [Ferrer, Isidre] Univ Barcelona, Hosp Llobregat, Inst Neuropatol, IDIBELL Hosp Univ Bellvitge,CIBERNED, Barcelona, Spain

3CELL MOL LIFE SCI 67 (22):3865-3882

Alterations on monoamines concentration in rat hippocampus produced by lipoic acid

2010 220,83Santos, IMS; de Freitas, RLM;Saldanha, GB; Tome, AD; Jordan, J; de Freitas, RM

[de Sales Santos, Itala Monica; de Freitas, Rivelilson Mendes] Univ Fed Piaui, Lab Expt Res Biol Sci, Picos, PI, Brazil; [Mendes de Freitas, Rizangela Lyne; Saldanha, GlaucioBarros] Catholic Fac Rainha Sertao, Course Pharm, Quixada, CE, Brazil; [Tome, Adriana da Rocha] Univ Estadual Ceara, Fortaleza, Ceara, Brazil; [Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Ctr Reg Invest Biomed, Grp Neurofarmacol,Dept Ciencias Med, Albacete, Spain

5ARQ NEURO-PSIQUIAT 68 (3):362-366

Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells

2010 864,35Pizarro, JG; Junyent, F; Verdaguer,E; Jordan, J; Beas-Zarate, C; Pallas, M; Camins, A; Folch, J

[Pizarro, Javier G.; Junyent, Felix; Verdaguer, Ester; Pallas,Merce; Camins, Antoni] Univ Barcelona, Fac Farm, Unitat Farmacol & Farmacognosia,Nucli Univ Pedrai, Inst Biomed IBUB,Ctr Invest Biomed Red Enfermedad, E-08028 Barcelona, Spain; [Junyent, Felix; Folch, Jaume] Univ Rovira & Virgili, Unitat Bioquim, Fac Med & Ciencies Salut, Ctr Invest Biomed Red Enfermedades Neurodegenerat,Tarragona 43201, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol,Albacete, Spain; [Beas-Zarate, Carlos] Univ Guadalajara, Lab Desarrollo & Regenerac Neural, Inst Neurobiol, Dept Biol Celular & Mol,CUCBA, Guadalajara 44430, Jalisco, Mexico


Viability of Saccharomyces cerevisiae cells following exposure to H2O2 and protective effect of minocycline depend on the presence of VDAC

2010 744,25Karachitos, A; Galganska, H;Baranek, M; Budzinska, M; Jordan,J; Kmita, H

[Karachitos, A.; Baranek, M.; Budzinska, M.; Kmita, H.] Adam Mickiewicz Univ Poznan, Fac Biol, Inst Mol Biol & Biotechnol, Lab Bioenerget, Poznan, Poland; [Jordan, J.] Univ Castilla La Mancha, Centro Reg Investigac Biomed, Fac Med, Dept Ciencias Med,Grp Neurofarmacol, Albacete, Spain

0FEBS J 277 ():286-286

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Viability of Saccharomyces cerevisiae cells following exposure to H2O2 and protective effect of minocycline depend on the presence of VDAC

2010 854,62Karachitos, A; Galganska, H;Baranek, M; Budzinska, M; Jordan,J; Kmita, H

[Karachitos, Andonis; Galganska, Hanna; Baranek, Malgorzata; Budzinska, Malgorzata; Kmita, Hanna] Adam Mickiewicz Univ Poznan, Fac Biol, Inst Mol Biol & Biotechnol, Lab Bioenerget, Poznan, Poland; [Jordan, Joaquin] UnivCastilla La Mancha, Ctr Reg Invest Biomed, Fac Med, Dept Ciencias Med,Grp Neurofarmacol, Albacete, Spain

0BBA-BIOENERGETICS 1797 ():68-68

Phosphodiesterase 5 inhibitors prevent 3,4-methylenedioxymethamphetamine-induced 5-HTdeficits in the rat

2009 723,97Puerta, E; Hervias, I; Goni-Allo, B;Lasheras, B; Jordan, J; Aguirre, N

[Puerta, Elena; Hervias, Isabel; Goni-Allo, Beatriz; Lasheras, Berta; Aguirre, Norberto] Univ Navarra, Sch Med, DeptPharmacol, Pamplona 31008, Spain; [Jordan, Joaquin] UnivCastilla La Mancha, Sch Med, Dept Med Sci, GrpNeuropharmacol,Reg Ctr Biomed Res, Albacete, Spain;[Aguirre, Norberto] Univ Navarra, Sch Med, CIMA, Div Neurosci, Pamplona 31008, Spain

18J NEUROCHEM 108 (3):755-766

Cholinesterase activity in brain ofsenescence-accelerated-resistant mouse SAMR1 andits variation in brain of senescence-accelerated-prone mouse SAMP8


[Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, E-02006 Albacete, Spain; [Jose Fernandez-Gomez, Francisco; Munoz-Delgado,Encarnacin; Fernanda Montenegro, Maria; Campoy, Francisco J.; Vidal, Cecilio J.] Univ Murcia, Dept Bioquim &Biol Mol A, Murcia, Spain

7

A molecular study of pathways involved in theinhibition of cell proliferation in neuroblastoma B65 cells by the GSK-3 inhibitors lithium and SB-415286

2009 854,75Pizarro, JG; Folch, J; Esparza, JL;Jordan, J; Pallas, M; Camins, A

[Camins, Antoni] Univ Barcelona, Unitat Farmacol & Farmacognosia, Ctr Invest Biomed Red Enfermedades Neurodegenerat, CIBERNED,Ins t Biomed,Fac Farm,Nucli Univ Pedralbe, E-08028 Barcelona, Spain; [Folch, Jaume] Univ Rovira & Virgili, Fac Med & Ciencies Salut, Ctr Invest Biomed Red Enfermedades Neurodegenerat, CIBERNED,Tarragona, Spain; [Folch, Jaume] Univ Rovira & Virgili, Unitat Bioquim, Tarragona, Spain; [Luis Esparza, Jose] Univ Rovira & Virgili, Fac Med & Ciencies Salut, Unitat Toxicol, Tarragona, Spain; [Jordan, J.] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete, Spain

9J CELL MOL MED 13 (9B):3906-3917

Mitochondria and calcium flux as targets of neuroprotection caused by minocycline in cerebellar granule cells

2009 894,58Garcia-Martinez EM;Sanz-BlascoS;Karachitos A;BandezMJ;Fernandez-Gomez FJ;Perez-Alvarez S;de MeraRM;Jordan MJ;Aguirre N;GalindoMF;Villalobos C;Navarro A;KmitaH;Jordan J;

Neurofarmacologia, Dpto Ciencias Medicas, Facultad de Medicina, UCLM, Albacete, Spain; Servicio de Farmacia Hospitalaria, Complejo Hospitalario Universitario de Albacete,Albacete, Spain

n.d.

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Age-related expression of adenosine receptors in brain from the senescence-accelerated mouse

2009 803,91Castillo, CA; Albasanz, JL; Leon, D;Jordan, J; Pallas, M; Camins, A;Martin, M

[Castillo, C. A.; Albasanz, J. L.; Leon, D.; Martin, M.] UnivCastilla La Mancha, Fac Quim, CRIB,Area Bioquim, Dept Quim Inorgan Organ & Bioquim, E-13071 Ciudad Real, Spain; [Jordan, J.] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, CRIB, Albacete, Spain; [Pallas, M.; Camins, A.] Nucli Univ Pedralbes, Univ Barcelona,Fa Farm, Ctr Invest Biomed Red Enfermedades Neurodegenerat, Unitat Farmacol & Formacognosia,Inst Biomed IBUB, Barcelona 08028, Spain

13EXP GERONTOL 44 (6-7):453-461

Lactacystin requires reactive oxygen species and Bax redistribution to induce mitochondria-mediated cell death

2009 925,07Perez-Alvarez, S; Solesio, ME;Manzanares, J; Jordan, J; Galindo,MF

[Solesio, Maria E.; Galindo, Maria F.] Univ Albacete, ComplejoHosp, Unidad Pfizer Castilla La Mancha Neuropsicofarmac,Albacete 02003, Spain; [Perez-Alvarez, Sergio; Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete, Spain; [Manzanares, Jorge] Univ Miguel Hernandez, Inst Neurociencias Alicante, CSIC, Alicante, Spain


Lipoic acid blocks seizures induced by pilocarpine via increases in delta-aminolevulinic dehydratase and Na(+), K(+)-ATPase activity in rat brain

2009 602,61de SS;da Rocha TA;Feitosa CM;deSouza GF;Feng D;de FreitasRM;Jordan J;

Laboratory of Experimental Research in Biological Sciences of Federal University of Piaui, Piaui, Brazil

n.d.

[Evaluation of the p53 Arg72Pro polymorphism as a prognostic factor in severe head injury and the inclusion of this indicator in a predictive model]

2009 Martinez LP;Carbayo HerenciaJA;Moreno CJ;Jordan J;GarciaC;Escribano MJ;

Departamento Anestesiologia, Reanimacion y Terapia del Dolor. Hospital General Universitario de Albacete. [email protected]

0Rev Esp Anestesiol Reanim 56 ():529-535

Oxidative stress-induced DNA damage and cell cycle regulation in B65 dopaminergic cell line

2009 613,28Pizarro, JG; Folch, J; Vazquez De laTorre, A; Verdaguer, E; Junyent, F;Jordan, J; Pallas, M; Camins, A

[Pizarro, Javier G.; Vazquez De la Torre, Aurelio; Verdaguer,Ester; Junyent, Felix; Pallas, Merce; Camins, Antoni] Univ Barcelona, Nucli Univ Pedralbes, Inst Biomedicina IBUB,Facultat Farm, Barcelona, Spain; [Folch, Jaume] Univ RoviraVirgili, Facultat Medicina Ciencies Salut, Centro Investigac Biomed Red Enfermedades Neurode, Unitat Bioquim, Reus, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Facultad Medicina, Dept Ciencias Medicas, Grupo Neurofarmacologia,Albacete, Spain; [Pizarro, Javier G.; Vazquez De la Torre, Aurelio; Verdaguer, Ester; Junyent, Felix; Pallas, Merce; Camins, Antoni] Univ Barcelona, Fac Farm, Unitat Farmacol & Farmacognosia, Inst Biomed IBUB,CIBERNED,Nuc li Univ Pedralbes, E-08028 Barcelona, Spain; [Folch, Jaume] UnivRovira & Virgili, CIBERNED, Fac Med & Ciencies Salut, Unitat Bioquim, Tarragona 43201, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete, Spain

9FREE RADICAL RES 43 (10):985-994

Cholinesterase activity in brain ofsenescence-accelerated-resistant mouse SAMR1 andits variation in brain of senescence-accelerated-prone mouse SAMP8

2009 532,97Fernandez-Gomez FJ;Munoz-Delgado E;MontenegroMF;Campoy FJ;Vidal CJ;Jordan J;

Grupo de Neurofarmacologia, Departamento de Ciencias Medicas, Universidad de Castilla-La Mancha, Albacete, Spain

n.d.

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Superoxide dismutases: a physiopharmacological update

2009 371,65Valdivia, A; Perez-Alvarez, S;Aroca-Aguilar, JD; Ikuta, I; Jordan, J

[Valdivia, A.; Perez-Alvarez, S.; Jordan, J.] UCLM, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete, Spain; [Aroca-Aguilar, J. D.] UCLM, Fac Med, Dept Genet, Albacete, Spain; [Ikuta, I.] SUNY Upstate Med Univ, Coll Med, Syracuse, NY 13210 USA; [Jordan, J.] UCLM, Ctr Reg Invest Biomed, Albacete, Spain


BAX and BAK proteins are required forcyclin-dependent kinase inhibitory drugs to cause apoptosis

2008 855,60Garrofe-Ochoa, X; de Mera, RMMF;Fernandez-Gomez, FJ; Ribas, J;Jordan, J; Boix, J

[Garrofe-Ochoa, Xenia; Ribas, Judit; Boix, Jacint] Univ Lleida,Dept Expt Med, Mol Pharmacol Lab, IRBLLEIDA, Catalonia25008, Spain; [Melero-Fernandez de Mera, Raquel M.;Fernandez-Gomez, Franciso J.; Jordan, Joaquin] UnivCastilla La Mancha, Fac Med, Ctr Reg Invest Biomed, GrpNeurofarmacol,Dept Ciencias Med, Albacete, Spain

10MOL CANCER T HER 7 (12):3800-3806

The level of butyrylcholinesterase activity increasesand the content of the mRNA remains unaffected in brain of senescence-accelerated mouse SAMP8


[Munoz-Delgado, Encarnacion; Fernanda Montenegro, Maria;Campoy, Francisco J.; Vidal, Cecilio J.] Univ Murcia, Dept Bioquim & Biol Mol A, E-30071 Murcia, Spain; [Jose Fernandez-Gomez, Francisco; Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete, Spain

4CHEM-BIOL INTER 175 (1-3):332-335

6-hydroxydopamine activates the mitochondrialapoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA

2008 723,97Gomez-Lazaro, M; Galindo, MF;Concannon, CG; Segura, MF;Fernandez-Gomez, FJ; Llecha, N;Comella, JX; Prehn, JHM; Jordan, J

[Gomez-Lazaro, Maria; Galindo, Maria F.; Fernandez-Gomez, Francisco J.; Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete 02006, Spain; [Concannon, Caoimhin G.; Prehn, Jochen H. M.] Royal Coll Surgeons Ireland, Dept Physiol, Dublin 2, Ireland; [Concannon, Caoimhin G.; Prehn, Jochen H. M.]Royal Coll Surgeons Ireland, RCSI Neurosci Res Ctr, Dublin 2, Ireland; [Segura, Miguel F.; Comella, Joan X.] Univ Lleida, Dept Ciencies Med Basiques, Cell Signaling & Apoptosis Grp, Lleida, Spain; [Comella, Joan X.] Hosp Arnau Vilanova, Lleida, Spain; [Llecha, Nuria] Hosp Arnau Vilanova, DeptPathol & Mol Genet, Lleida, Spain; [Jordan, Joaquin] Ctr Reg Investigac Biomed, Albacete, Spain

59J NEUROCHEM 104 (6):1599-1612

Minoxidil prevents3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK

2008 723,97Goni-Allo, B; Puerta, E; Ramos, M; Lasheras, B; Jordan, J; Aguirre, N

[Goni-Allo, Beatriz; Puerta, Elena; Ramos, Maria; Lasheras, Berta; Aguirre, Norberto] Univ Navarra, Fac Med, Dept Pharmacol, Sch Med, Pamplona 31008, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Reg Ctr Biomed Res, Dept Med Sci, Grp Neuropharmacol, Albacete, Spain; [Aguirre, Norberto] Univ Navarra, Sch Med, CIMA, Div Neurosci, E-31080 Pamplona, Spain

14J NEUROCHEM 104 (4):914-925

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6-Hydroxydopamine (6-OHDA) inducesDrp1-dependent mitochondrial fragmentation in SH-SY5Y cells

2008 875,27Gomez-Lazaro, M; Bonekamp, NA;Galindo, MF; Jordan, J; Schrader, M

[Gomez-Lazaro, Maria; Galindo, Maria F.; Jordan, Joaquin]Univ Castilla La Mancha, Ctr Reg Invest Biomed, Grp Neurofarmacol, Dept Ciencias Med,Fac Med, Albacete 02006, Spain; [Gomez-Lazaro, Maria; Bonekamp, Nina A.; Schrader, Michael] Univ Aveiro, Ctr Cell Biol, P-3800 Aveiro, Portugal; [Gomez-Lazaro, Maria; Bonekamp, Nina A.; Schrader, Michael] Univ Aveiro, Dept Biol, P-3800 Aveiro, Portugal; [Galindo, Maria F.] Complejo Hosp Univ Albacete, Unidad Pfizer Castilla La Mancha Neuropsicofarmac, Albacete, Spain

63FREE RADICAL BIO L MED 44 (11):1960-1969

Inflammation as Therapeutic Objective in Stroke2008 753,31Jordan, J; Segura, T; Brea, D;Galindo, MF; Castillo, J

[Jordan, Joaquin] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol,Ctr Reg Invest Biomed, Albacete 02006, Spain; [Segura, Tomas] Complejo Hosp UnivAlbacete, Serv Neurol, Albacete, Spain; [Brea, David; Castillo, Jose] Univ Santiago de Compostela, Hosp Clin, Dept Neurol, Clin Neurosci Res Lab, Santiago De Compostela, Spain; [Galindo, Maria F.] Complejo Hosp Univ Albacete, Unidad Neuropsicofarmacol Translac, Albacete, Spain

39CURR PHARM DESIG N 14 (33):3549-3564

Is good old minocycline a new neuroprotective drug?2008 201,18de Mera, RMMF; Garcia-Martinez, E;Fernandez-Gomez, FJ;Hernandez-Guijo, JM; Aguirre, N;Galindo, ME; Jordan, J

[Melero-Fernandez de Mera, R. M.; Fernandez-Gomez, F. J.;Jordan, J.] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, E-02006 Albacete, Spain; [Garcia-Martinez, E.] Complejo Hosp Univ Albacete, Serv Farmacia, Albacete, Spain; [Hernandez-Guijo, J. M.] UnivAutonoma Madrid, Fac Med, Dept Farmacol & Terapeut, Inst Teofilo Hernando, Madrid, Spain; [Aguirre, N.] Univ Navarra,Fac Med, Dept Farmacol, E-31080 Pamplona, Spain;[Galindo, M. E.] Complejo Hosp Univ Albacete, Unidad Pfizer Castilla La Mancha Neuropsicofarmac, Albacete, Spain;[Melero-Fernandez de Mera, R. M.; Fernandez-Gomez, F. J.;Jordan, J.] Ctr Reg Invest Biomed, Grp Neurofarmacol, Albacete, Spain


Recommendations and treatment strategies for themanagement of acute ischemic stroke

2008 682,86Segura, T; Calleja, S; Jordan, J [Segura, Tomas] Hosp Gen Univ Albacete, Dept Neurol,Albacete 02006, Spain; [Segura, Tomas] Univ Castilla LaMancha, Dept Med Sci, Fac Med, Albacete 02006, Spain; [Calleja, Sergio] Univ Hosp Cent Asturias, Dept Neurol,Oviedo, Spain; [Jordan, Joaquin] Univ Castilla La Mancha, Grp Neurofarmacol, Fac Med, Albacete 02006, Spain

23EXPERT OPIN PHARMACOTHER 9 (7):1071-1085

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Pharmacology of neuroprotection in acute ischemicstroke

2008 201,18Fernandez-Gomez, FJ; Hernandez, F;Argandona, L; Galindo, MF; Segura,T; Jordan, J

[Jordan, J.] Univ Castilla La Mancha, Fac Med, Dept CienciasMed Farmacol, Grp Neurofarmacol, E-02006 Albacete, Spain;[Hernandez, F.; Argandona, L.; Segura, T.] Hosp Gen Univ Albacete, Serv Neurol, Albacete, Spain; [Galindo, M. F.]Complejo Hosp Univ Albacete, Unidad Pfizer Castilla La Mancha Neuropsicofarmac, Albacete, Spain; [Jordan, J.] Ctr Reg Invest Biomed, Grp Neurofarmacol, Albacete, Spain


BAX and BAK proteins are required forcyclin-dependent kinase inhibitory drugs to cause apoptosis

2008 855,60Garrofe-Ochoa, X; de Mera, RMMF;Fernandez-Gomez, FJ; Ribas, J;Jordan, J; Boix, J

[Garrofe-Ochoa, Xenia; Ribas, Judit; Boix, Jacint] Univ Lleida,Dept Expt Med, Mol Pharmacol Lab, IRBLLEIDA, Catalonia25008, Spain; [Melero-Fernandez de Mera, Raquel M.;Fernandez-Gomez, Franciso J.; Jordan, Joaquin] UnivCastilla La Mancha, Fac Med, Ctr Reg Invest Biomed, GrpNeurofarmacol,Dept Ciencias Med, Albacete, Spain

10MOL CANCER T HER 7 (12):3800-3806


2008 854,75Pizarro JG;Folch J;EsparzaJL;Jordan J;Pallas M;Camins A;

Unitat de Farmacologia i Farmacognosia, Institut de Biomedicina and Centros de Investigacion Biomedica en Redde Enfermedades Neurodegenerativas (CIBERNED), Facultat de Farmacia, Universitat de Barcelona, Nucli Universitari de Pedralbes, 08028 Barcelona, Spain

n.d.


2008 854,75Pizarro JG;Folch J;EsparzaJL;Jordan J;Pallas M;Camins A;

Unitat de Farmacologia i Farmacognosia, Institut de Biomedicina and Centros de Investigacion Biomedica en Redde Enfermedades Neurodegenerativas (CIBERNED), Facultat de Farmacia, Universitat de Barcelona, Nucli Universitari de Pedralbes, 08028 Barcelona, Spain

n.d.

THE MOLECULAR BASIS OF HOW LACTACYSTINACTIVATES THE MITOCHONDRIAL-MEDIAT EDAPOPTOTICAL PATHWAY

2008 150,77Perez-Alvarez, S; Solesio, ME;Manzanares, J; Leiva, C; Jordan, J;Galindo, MF

[Perez-Alvarez, S.; Jordan, J.] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, E-13071 Ciudad Real, Spain; [Manzanares, J.] UMH CSIC, Madrid, Spain; [Leiva, C.] Hosp Gen Alicante, Alicante, Spain

0METHOD FIND EXP CLIN 30 ():67-67

Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca2+ signalling in hippocampal neurons

2007 693,75Gonzalez, JC; Egea, J; Godino, MD;Fernandez-Gomez, FJ;Sanchez-Prieto, J; Gandia, L; Garcia,AG; Jordan, J; Hernandez-Guijo, JM

Univ Autonoma Madrid, Inst Teofilo Hernando, E-28029 Madrid, Spain; Univ Autonoma Madrid, Fac Med, Dept Farmacol & Terapeut, E-28029 Madrid, Spain; Univ Complutense, Fac Vet, Dept Bioquim, Madrid, Spain; Univ Autonoma Madrid, Fac Med, Hosp Univ Princesa, Serv Farmacol Clin, Madrid, Spain; Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete, Spain; Ctr Reg Invest Biomed, Albacete, Spain

38EUR J NEUROSCI 26 (9):2481-2495

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Reactive oxygen species and p38 mitogen-activated protein kinase activate bax to induce mitochondrialcytochrome c release and apoptosis in response to malonate

2007 874,41Gomez-Lazaro, M; Galindo, MF; deMera, RMMF; Fernandez-Gomez, FJ;Concannon, CG; Segura, MF;Comella, JX; Prehn, JHM; Jordan, J

Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Grp Neurofarmacol, Albacete 02006, Spain; Royal Coll Surgeons Ireland, Dept Physiol, Dublin 2, Ireland; Royal Coll Surgeons Ireland, Ctr Res Neurosci, RCSI, Dublin 2, Ireland; Univ Lleida, Dept Ciencias Med Basiques, Cell Signaling & Apoptosis Grp, Lleida, Spain; Hosp Arnau Vilanova, Lleida, Spain; Ctr Reg Invest Biomed, Albacete, Spain

85MOL PHARMACOL 71 (3):736-743

The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging

2007 723,19Llorens, S; de Mera, RMMF; Pascual,A; Prieto-Martin, A; Mendizabal, Y;de Cabo, C; Nava, E; Jordan, J

Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Albacete, Spain; Univ Castilla La Mancha, Ctr Reg Invest Biomed, Albacete, Spain; Ctr Reg Invest Biomed, Grp Neurofarmacol, Albacete, Spain; Univ Albacete, Serv Anat Patol, Complejo Hosp, Albacete, Spain; Univ Albacete, Unidad Invest, Complejo Hosp, Albacete, Spain

13BIOGERONTOLOGY 8 (6):663-672

Minocycline and cytoprotection: shedding new light on a shadowy controversy.

2007 Jordan J;Fernandez-GomezFJ;Ramos M;Ikuta I;AguirreN;Galindo MF;

Grupo de Neurofarmacologia, Departamento de Ciencias Medicas, Facultad de Medicina, Universidad de Castilla-La Mancha, Albacete, Spain. [email protected]

0Curr Drug Deliv 4 (3):225-31

Stroke pathophysiology: management challenges and new treatment advances

2007 371,65Jordan, J; Ikuta, I; Garcia-Garcia, J;Calleja, S; Segura, T

[Jordan, J.; Segura, T.] Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, E-13071 Ciudad Real, Spain; [Ikuta, I.] SUNY Upstate Med Univ, Coll Med, Syracuse, NY USA; [Calleja, S.] Hosp Univ Cent Asturias, Dept Neurol, Oviedo, Spain; [Jordan, J.] Univ Castilla La Mancha, Ctr Reg Invest Biomed, Grp Neurofarmacol, E-13071 Ciudad Real, Spain


Pyruvate protects cerebellar granular cells from6-hydroxydopamine-induced cytotoxicity by activatingthe Akt signaling pathway and increasing glutathione peroxidase expression

2006 875,62Fernandez-Gomez, FJ; Pastor, MD;Garcia-Martinez, EM; de Mera, RMF;Gou-Fabregas, M; Gomez-Lazaro, M;Calvo, S; Soler, RM; Galindo, MF;Jordan, J

Univ Castilla La Mancha, CRIB, Fac Med, Grp Neurofarmacol, Albacete 02006, Spain; Univ Castilla La Mancha, Dept Ciencias Med, Fac Med, Albacete 02006,Spain; Univ Castilla La Mancha, Grp Glia & Isquemia,Albacete 02006, Spain; Complejo Hosp Univ Albacete, Serv Farm, Albacete, Spain; Ctr Reg Invest Biomed, Albacete, Spain

26NEUROBIOL DISEASE 24 (2):296-307

Atheroma development in apolipoprotein E-null mice isnot regulated by phosphorylation of p27(Kip1) on threonine 187.

2006 573,06n.d.J CELL BIOCHEM 97 (4):735-743

Malonate induces cell death via mitochondrial potential collapse and delayed swelling through an ROS-dependent pathway

2005 925,07Fernandez-Gomez, FJ; Galindo, MF;Gomez-Lazaro, M; Yuste, VJ;Comella, JX; Aguirre, N; Jordan, J

Univ Castilla La Mancha, Fac Med, Ctr Reg Invest Biomed, Dept Ciencias Med, Albacete 02006, Spain; Univ Lleida, Grp Neurobiol Mol, Dept Ciencies Med Basiques, Lleida, Spain;Univ Navarra, Dept Farmacol, Fac Med, E-31080 Pamplona,Spain; Ctr Reg Invest Biomed, Albacete, Spain


In vivo studies on the protective role of minocyclineagainst excitotoxicity caused by malonate or N-methyl-D-aspartate

2005 814,65Goni-Allo, B; Ramos, M; Jordan, J;Aguirre, N

Univ Navarra, Fac Med, Dept Farmacol, Pamplona 31008, Spain; Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Albecete, Spain; Ctr Reg Invest Biomed, Albacete, Spain; CIMA, Pamplona, Spain

11EXP NEUROL 191 (2):326-330

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Involvement of mitochondrial potential and calcium buffering capacity in minocycline cytoprotective actions

2005 563,12Fernandez-Gomez, FJ; Galindo, MF;Gomez-Lazaro, M; Gonzalez-Garcia,C; Cena, V; Aguirre, N; Jordan, J

Univ Castilla La Mancha, Dept Ciencias Med, Fac Med, Albacete 02006, Spain; Univ Castilla La Mancha, CSIC, Unidad Asociada Neurodeath, Dept Ciencias Med, Albacete02006, Spain; Univ Navarra, Ctr Invest Med Aplicada, DeptFarmacol, E-31080 Pamplona, Spain

36NEUROSCIENCE 133 (4):959-967

The role of mitochondria molecular and cellular pathways involved in Parkinson’s disease.

2005 150,77n.d.METHOD FIND EXP CLIN 27 (2):193-195

Minocycline fails to protect cerebellar granular cellcultures against malonate-induced cell death

2005 875,62Fernandez-Gomez, FJ;Gomez-Lazaro, M; Pastor, D; Calvo,S; Aguirre, N; Galindo, MF; Jordan, J

Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Albacete 02006, Spain; Univ Navarra, Fac Med, Dept Farmacol, E-31080 Pamplona, Spain

23NEUROBIOL DISEASE 20 (2):384-391

Activation of p53 and the pro-apoptotic p53 target gene PUMA during depolarization-induced apoptosisof chromaffin cells

2005 814,65Gomez-Lazaro, M; Galindo, MF;Fernandez-Gomez, FJ; Prehn, JHM;Jordan, J

Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Albacete 02006, Spain; Royal Coll Surgeons Ireland, Dept Physiol, Dublin 2, Ireland; Royal Coll Surgeons Ireland, RCSI, Neurosci Res Ctr, Dublin 2, Ireland

11EXP NEUROL 196 (1):96-103

p53: Twenty five years understanding the mechanism of genome protection

2004 371,65Gomez-Lazaro, M;Fernandez-Gomez, FJ; Jordan, J

Univ Castilla La Mancha, Fac Med, Ctr Reg Invest Biomed, Almansa 02006, Albacete, Spain


Glitazones differentially regulate primary astrocyte andglioma cell survival - Involvement of reactive oxygen species and peroxisome proliferator-activatedreceptor-gamma

2004 794,65Perez-Ortiz, JM; Tranque, P;Vaquero, CF; Domingo, B; Molina, F;Calvo, S; Jordan, J; Cena, V; Llopis,J

Univ Castilla La Mancha, Fac Med, Physiol Unit, Albacete 02006, Spain; Univ Castilla La Mancha, Ctr Reg Invest Biomed, Albacete 02006, Spain

90J BIOL CHEM 279 (10):8976-8985

Bcl-x(L) blocks mitochondrial multiple conductancechannel activation and inhibits 6-OHDA-induced deathin SH-SY5Y cells

2004 723,97Jordan, J; Galindo, MF; Tornero, D;Gonzalez-Garcia, C; Cena, V

Univ Castilla La Mancha, Ctr Reg Invest Biomed, Albacete 02071, Spain

49J NEUROCHEM 89 (1):124-133

The serine proteases and their function in neuronaldeath processes

2004 201,18Fuster-Lluch, O; Galindo, MF; Cena,V; Jordan, J

Univ Castilla La Mancha, Ctr Reg Invest Biomed, E-02071 Albacete, Spain; Complejo Hosp Univ Albacete, Serv Anal Clin, Albacete, Spain


[The role of protein p53 in neurodegenerative processes throughout the 25 years of its history]

2004 201,18Gomez-Lazaro, M;Fernandez-Gomez, FJ; Jordan, J

Univ Castilla La Mancha, Ctr Reg Invest Biomed, Dept Ciencias Med, Fac Med, E-02006 Albacete, Spain

3Rev Neurol 39 (3):243-50

Glitazones differentially regulate primary astrocyte andglioma cell survival. Involvement of reactive oxygenspecies and peroxisome proliferator-activatedreceptor-gamma

2004 794,65Perez-Ortiz JM;Tranque P;VaqueroCF;Domingo B;Molina F;CalvoS;Jordan J;Cena V;Llopis J;

Physiology Unit, Facultad de Medicina, and Centro Regional de Investigaciones Biomedicas, Universidad de Castilla-La Mancha, 02006 Albacete, Spain

n.d.J Biol Chem 279 (10):8976-8985

Pharmacological targets in neurodegenerativediseases

2003 201,18Segura, T; Galindo, MF;Rallo-Gutierrez, B; Cena, V; Jordan,J

Univ Castilla La Mancha, Edificio Fac Med, Ctr Reg Invest Biomed, Dept Ciencias Med, E-02071 Albacete, Spain; UnivAlbacete, Gen Hosp, Serv Neurol, Albacete, Spain

0REV NEURO LOGIA 36 (11):1047-1057

Chromaffin cell death induced by 6-hydroxydopamine is independent of mitochondrial swelling and caspaseactivation

2003 723,97Galindo, MF; Jordan, J;Gonzalez-Garcia, C; Cena, V

Univ Castilla La Mancha, Ctr Reg Invest Biomed, Fac Med, Albacete 02071, Spain; Univ Castilla La Mancha, Dpto Ciencias Med, Fac Med, Albacete 02071, Spain

30J NEUROCHEM 84 (5):1066-1073

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Mitochondrial dysfunction is involved in apoptosisinduced by serum withdrawal and fatty acids in the beta-cell line Ins-1

2003 814,72Maestre, I; Jordan, J; Calvo, S; Reig,JA; Cena, V; Soria, B; Prentki, M;Roche, E

Univ Miguel Hernandez, Inst Bioingn, Div Nutr, Alicante 03550, Spain; Univ Castilla La Mancha, Fac Med, Ctr Reg Invest Biomed, Albacete 02071, Spain; Univ Castilla La Mancha, Fac Med, Dept Ciencias Med, Albacete 02071,Spain; Univ Montreal, Mol Nutr Unit, Dept Nutr, Montreal, PQ H2L 4M1, Canada; Univ Montreal, Mol Nutr Unit, DeptBiochem, Montreal, PQ H2L 4M1, Canada; CR CHUM, Montreal, PQ H2L 4M1, Canada

121ENDOCRINOLOGY 144 (1):335-345

Reactive oxygen species induce swelling andcytochrome c release but not transmembranedepolarization in isolated rat brain mitochondria

2003 925,07Galindo, MF; Jordan, J;Gonzalez-Garcia, C; Cena, V

Univ Castilla La Mancha, Ctr Reg Invest Biomed, Albacete 02071, Spain


Role and regulation of p53 in depolarization-inducedneuronal death

2003 563,12Jordan, J; Galindo, MF;Gonzalez-Garcia, C; Cena, V

Univ Castilla La Mancha, Ctr Reg Invest Biomed, Edif Fac Med, Albacete 02071, Spain

35NEUROSCIENCE 122 (3):707-715

Mitochondrial control of neuron death and its role in neurodegenerative disorders

2003 371,65Jordan, J; Cena, V; Prehn, JHM Univ Castilla La Mancha, Ctr Reg Invest Biomed, Albacete, Spain; Univ Castilla La Mancha, Fac Med, Dpto Ciencias Med, Albacete, Spain; Royal Coll Surgeons Ireland, Dept Physiol, Dublin 2, Ireland


Superoxide anions mediate veratridine-induced cytochrome c release and caspase activity in bovine chromaffin cells

2002 925,07Jordan, J; Galindo, MF; Tornero, D;Benavides, A; Gonzalez, C; Agapito,MT; Gonzalez-Garcia, C; Cena, V

Univ Castilla La Mancha, Ctr Reg Invest Biomed, Albacete 02071, Spain; Univ Castilla La Mancha, Fac Med, Dpto Ciencias Med, Albacete 02071, Spain; Fac Med, DeptBioquim Biol Mol & Fisiol, Valladolid, Spain


Calcium-activated pathways in neuronal death2000 150,77Jordan, J; Galindo, MF; Cespedes,MV; Gonzalez-Garcia, C; Cena, V

Univ Castilla La Mancha, Fac Med, Dept Med Sci, Albacete, Spain

0METHOD FIND EXP CLIN 22 (6):399-400

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