algunas aportaciones de patólogos mexicanos a la anatomía … · 2013-07-11 · algunas...
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Algunas aportaciones de patoacutelogos mexicanos a
la Anatomiacutea Patoloacutegica actual
Reynaldo Falcoacuten Escobedo
Facultad de Medicina Universidad Autoacutenoma de San Luis Potosiacute
Hospital Central Dr Ignacio Morones Prieto
San Luis Potosiacute SLP
MEacuteXICO
Dr Isaac Costero Tudanca
Dr Ruy Peacuterez Tamayo
Dr Jorge Albores Saavedra
CARCINOMAS DEL CUELLO UTERINO CON PATROacuteN PAPILAR
bull Carcinoma de ceacutelulas transicionales puro
bull Carcinoma de ceacutelulas transicionales con carcinoma epidermoide
bull Carcinoma de ceacutelulas transicionales con adenocarcinoma
bull Carcinoma epidermoide
bull Carcinoma verrucoso
CARCINOMA DE CEacuteLULAS TRANSICIONALES DEL CUELLO UTERINO
bull Afecta a mujeres cuyas edades oscilan entre 34 y 81 antildeos
bull El cuadro cliacutenico es similar al del carcinoma epidermoide
bull Puede ser exofiacutetico o polipoide
bull Su tamantildeo es variable (2 a 6 cm)
bull Metaacutestasis 38 casos
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dr Isaac Costero Tudanca
Dr Ruy Peacuterez Tamayo
Dr Jorge Albores Saavedra
CARCINOMAS DEL CUELLO UTERINO CON PATROacuteN PAPILAR
bull Carcinoma de ceacutelulas transicionales puro
bull Carcinoma de ceacutelulas transicionales con carcinoma epidermoide
bull Carcinoma de ceacutelulas transicionales con adenocarcinoma
bull Carcinoma epidermoide
bull Carcinoma verrucoso
CARCINOMA DE CEacuteLULAS TRANSICIONALES DEL CUELLO UTERINO
bull Afecta a mujeres cuyas edades oscilan entre 34 y 81 antildeos
bull El cuadro cliacutenico es similar al del carcinoma epidermoide
bull Puede ser exofiacutetico o polipoide
bull Su tamantildeo es variable (2 a 6 cm)
bull Metaacutestasis 38 casos
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dr Ruy Peacuterez Tamayo
Dr Jorge Albores Saavedra
CARCINOMAS DEL CUELLO UTERINO CON PATROacuteN PAPILAR
bull Carcinoma de ceacutelulas transicionales puro
bull Carcinoma de ceacutelulas transicionales con carcinoma epidermoide
bull Carcinoma de ceacutelulas transicionales con adenocarcinoma
bull Carcinoma epidermoide
bull Carcinoma verrucoso
CARCINOMA DE CEacuteLULAS TRANSICIONALES DEL CUELLO UTERINO
bull Afecta a mujeres cuyas edades oscilan entre 34 y 81 antildeos
bull El cuadro cliacutenico es similar al del carcinoma epidermoide
bull Puede ser exofiacutetico o polipoide
bull Su tamantildeo es variable (2 a 6 cm)
bull Metaacutestasis 38 casos
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dr Jorge Albores Saavedra
CARCINOMAS DEL CUELLO UTERINO CON PATROacuteN PAPILAR
bull Carcinoma de ceacutelulas transicionales puro
bull Carcinoma de ceacutelulas transicionales con carcinoma epidermoide
bull Carcinoma de ceacutelulas transicionales con adenocarcinoma
bull Carcinoma epidermoide
bull Carcinoma verrucoso
CARCINOMA DE CEacuteLULAS TRANSICIONALES DEL CUELLO UTERINO
bull Afecta a mujeres cuyas edades oscilan entre 34 y 81 antildeos
bull El cuadro cliacutenico es similar al del carcinoma epidermoide
bull Puede ser exofiacutetico o polipoide
bull Su tamantildeo es variable (2 a 6 cm)
bull Metaacutestasis 38 casos
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
CARCINOMAS DEL CUELLO UTERINO CON PATROacuteN PAPILAR
bull Carcinoma de ceacutelulas transicionales puro
bull Carcinoma de ceacutelulas transicionales con carcinoma epidermoide
bull Carcinoma de ceacutelulas transicionales con adenocarcinoma
bull Carcinoma epidermoide
bull Carcinoma verrucoso
CARCINOMA DE CEacuteLULAS TRANSICIONALES DEL CUELLO UTERINO
bull Afecta a mujeres cuyas edades oscilan entre 34 y 81 antildeos
bull El cuadro cliacutenico es similar al del carcinoma epidermoide
bull Puede ser exofiacutetico o polipoide
bull Su tamantildeo es variable (2 a 6 cm)
bull Metaacutestasis 38 casos
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
CARCINOMA DE CEacuteLULAS TRANSICIONALES DEL CUELLO UTERINO
bull Afecta a mujeres cuyas edades oscilan entre 34 y 81 antildeos
bull El cuadro cliacutenico es similar al del carcinoma epidermoide
bull Puede ser exofiacutetico o polipoide
bull Su tamantildeo es variable (2 a 6 cm)
bull Metaacutestasis 38 casos
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
CK7 CK20
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Carcinoma neuroendocrino de ceacutelulas grandes de
vesiacutecula biliar
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Carcinoma neuroendocrino de ceacutelulas grandes de la ampolla de Vater
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Carcinoma de ceacutelulas pequentildeas de la vesiacutecula biliar
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Carcinoma de ceacutelulas
pequentildeas
de la vesiacutecula biliar
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
The American Journal of Surgical Pathology 19(1)91-9 1995
Clear cell carcinomas of the gallbladder and
extrahepatic bile ducts
Celeste Vardam MD Jorge Albores-Saavdera MD
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Carcinoma cribiforme de vesiacutecula biliar
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Adenocarcinoma foveolar de viacuteas biliares extrahepaacuteticas
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Hiperplasia fisioloacutegica de
ceacutelulas C
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Ceacutelulas de Cajal en vesiacutecula biliar
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Neoplasia Intraepitelial
Pancreaacutetica de tipo Espumoso
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Papiloma urotelial invertido con
estructuras papilares
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Senos de Aschoff-Rokitansky asociados con
abundante moco extracelular simulando carcinoma
mucinoso
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Int J Gynecol Pathol 199716(3)291-3
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dr Alberto G Ayala
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Honorary member of the Mexican Association of Pathologists
Honorary member of the Spanish Society of Pathologists
Received the ldquoHarlan J Spjutrdquo award given by the Houston Society of Clinical Pathologists 1992-1993 This award is given annually to individuals who have demonstrated to be true scholars and teachers
Received the Ashbel Smith Professorship Award from M D Anderson Cancer Center 1996
Received the Charlie Lemaistre Oustanding Achievement Award from The University of Texas MD Anderson Cancer Center in September 1997
Award Annual meeting of The Radiological Society of North America ldquoCum Laude 0682MK Giant Cell Containing Lesions of Bone KW McEnery MD A Yasko MD AK Raymond MD AG Ayala MD November 29 to December 4 1998
Professor Emeritus Ashbel-Smith given by The University of Texas MD Anderson Cancer Center upon retirement 2000
Award Texas Society of Pathologist Annual Meeting Galveston Texas Prestigious Caldwell Award February 10 2001
The Distinguished Alumnus Award conferred by the University of Texas MD Anderson Cancer Center Houston Texas in December 18 2012
Award on ldquoExcellence in the Professional Development ldquoDistinguidhed (ldquoA la excelencia en el Desarrollo Profesional) conferred by the University of Nuevo Leon Monterrey Mexico September 18 2013
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
The Arthur Purdy Stout Recognition Award conferred by the Arthur Purdy
Stout Society USCAP
March 2013 Baltimore Marylan
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
403
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Artiacuteculos predilectos Entre otras publicaciones la descripcioacuten de la caacutepsula de la proacutestata y el artiacuteculo sobre ldquoClear cell cribriform hyperplasia of the prostate glandrdquo son publicaciones predilectas Asi como tambien hay otro artiacuteiculo publicado en Caacutencer sobre ldquoOsteosarcoma de ceacutelulas pequentildeasrdquo Otra publcacion muy apreciada es la descripcioacuten de la ldquoMuscularis Mucosaerdquo en la vejiga urinaria Hay muchas otras maacutes de las cuales tambien estoy muy orgulloso Otro ejemplo es el articulo ldquoChest wall hamartomardquo
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Am J Surg Pathol 1986 Oct10(10)665-71
Clear cell cribriform hyperplasia of prostate Report of 10 cases Ayala AG Srigley JR Ro JY Abdul-Karim FW Johnson DE Abstract We report 10 patients with clear cell cribriform hyperplasia of the prostate Their ages ranged from 62 to 87 years with a mean of 72 years The clinical diagnosis in all patients was benign nodular hyperplasia all the patients are alive and have shown no evidence of recurrent disease Follow-ups ranged from 1 month to 7 years (median 125 months mean 246 months) Pathologically this lesion has a cribriform arrangement of clear cells with a complex papillary growth simulating the cribriform pattern of prostatic carcinoma In fact in five of the 10 cases the referring diagnosis was either carcinoma or possible carcinoma Cytologically however there is no nuclear atypia mitosis or prominent nucleoli and typically there is a double epithelial cell layer at the periphery of the involved acini In summary clear cell cribriform hyperplasia is a benign hyperplastic process with a complex papillary-cribriform structure and should not be confused with prostatic carcinoma The key feature for the diagnosis is the preservation of nodular configuration with a bland cytology and
double cell layer lining the involved acini
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Cancer 1989 Nov 1564(10)2162-73
Small cell osteosarcoma A clinicopathologic study of 27 cases Ayala AG Ro JY Raymond AK Jaffe N Chawla S Carrasco H Link M Jimenez J Edeiken J Wallace S et al Department of Pathology University of Texas M D Anderson Cancer Center Houston 77030 Abstract We report a study of 27 patients with small cell osteosarcoma (SCO) 17 from the M D Anderson Cancer Center (MDAH) and ten from the Pediatric Oncology Group (POG) There were 12 male patients and 15 female patients 19 were white five were black and three were Hispanic They ranged from 6 to 28 years of age with a median of 14 years Histologically there were three patterns Ewings-like lymphoma-like and spindle cell All cases showed osteoid formation and a few had chondroid areas There was cytoplasmic glycogen in ten cases Initial treatment for MDAH patients included intraarterial infusion of cisplatin in ten amputation in four partial mandibulectomies in two and biopsy with local radiotherapy and systemic chemotherapy in one All POG patients had resection or amputation followed by adjuvant chemotherapy Twelve patients are alive of whom nine have had significant follow-ups for 25 to 90 months Fourteen patients are dead of lung spine and brain metastases from 1 to 23 months after initial diagnosis One patient is alive with lung relapse at 4 months In summary SCO is a high-grade variant of osteosarcoma with an incidence of up to 4 of all osteosarcomas that affects patients of the same age group and has the same anatomic location as conventional osteosarcoma Currently SCO appears to have a prognosis that is the same as or slightly worse than that of conventional osteosarcoma Furthermore although intraarterial infusion is effective for the primary tumors in the bone distant metastases are difficult to control
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dr Mario A Luna
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dr Joseacute Jessurun
Dra Leticia Quintanilla-Martiacutenez
Dra Leticia Quintanilla-Martiacutenez
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