Download - Diabetes Mellitus Internos
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DIABETES MELLITUS
GIOVANNI CAVIEDES PEREZ
MEDICINA INTERNA
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DIABETES CARE, VOLUME 30, SUPPLEMENT 1, JANUARY 2008
Definición
“Es un grupo de enfermedades metabólicas caracterizadas por hiperglicemia resultante del defecto en la secreción o acción de la insulina o ambas”.
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AACE Diabetes Mellitus Guidelines, Endocr Pract. 2007;13(Suppl 1) 2007
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AACE Diabetes Mellitus Guidelines, Endocr Pract. 2007;13(Suppl 1) 2007
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AACE Diabetes Mellitus Guidelines, Endocr Pract. 2007;13(Suppl 1) 2007
Epidemiología
76% hombres blancos 65% mujeres blancas 37% mujeres negras 68% hombres negros
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AACE Diabetes Mellitus Guidelines, Endocr Pract. 2007;13(Suppl 1) 2007
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AACE Diabetes Mellitus Guidelines, Endocr Pract. 2007;13(Suppl 1) 2007
Screening y diagnóstico
Todos los >30 años con factores de riesgo
No uso de HBA1c para diagnóstico
Test tolerancia oral: screening dx
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DIABETES CARE, VOLUME 30, SUPPLEMENT 1, JANUARY 2007
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DIABETES CARE, VOLUME 30, SUPPLEMENT 1, JANUARY 2007
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DIABETES CARE, VOLUME 30, SUPPLEMENT 1, JANUARY 2007
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N Engl J Med, Vol. 347, No. 17
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ENDOCRINE PRACTICE Vol 13 (Suppl 1) May/June 2007
Prevención Modificación del estilo de vida
Prediabetes
Hiperglicemia postprandial
Agentes farmacologicos
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DIABETES CARE, VOLUME 30, SUPPLEMENT 1, JANUARY 2008
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TRATAMIENTO BIGUANIDAS
SULFONILURIAS
INHIBIDORES DE ALGA GLUCOSIDASA
TIZD
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ENDOCRINE PRACTICE Vol 13 (Suppl 1) May/June 2007
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ENDOCRINE PRACTICE Vol 13 (Suppl 1) May/June 2007
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FARMACOCINETICA
THE NEW ENGLAND JOURNAL OF MEDICINE 2006INSULIN ANALOGUES
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TRATAMIENTO
HIPOGLICEMIA
CETOACIDOSIS DIABETICA ESTADO HIPEROSMOLAR
COMPLICACIONES CRÓNICAS