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    Chemistry & BiochemistryChapters 2 & 3

    Honors Biology

    Mrs. Gutierrez

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    Why study

    chemistry ina biology

    class? !"en the most basicunits o# li#e$ cells$are made o# smallerand smaller subunits

    %he structure and#unction o# allli"ing things are

    go"erned by thelas o# chemistry

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    What is Chemistry?

    %he study o# the composition$ structure$ properties$and reactions o# a substance.

    'll li#e processes in"ol"e chemical changes. (  )igestion (  *eproduction

     (  Groth

     ( *espiration

    +nce chemical changes are understood$ li#e processes can be better understood.

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    matter energy

    atoms mass

    elements

    ,2-,

    molecule

    compound

    structure

     proton neutron electron

    nucleus isotope ion

    hydrogen

     pH

    acid  base

    /ineticheat

    mo"ement'cti"ationenergy

    reactions

     potential

     position

    stored

     battery '%0

    chemical

     bonds

    ionic

    co"alenthydrogen

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    What is pH?

     pH stands #or the potential1poer o# thehydrogen ion H4

     p+H is the

     potential1poer o# thehydro5ide ion +H64

     pH and p+H add up to -7 (  !58 i# the p+H o# a solution

    is 9$ hat is the pH? (  ' pH o# 9 is considered

    neutral

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    http811.:ohn/yr/.com1pH.htm

    l

     pH scale ;uanti#ied

    http://www.johnkyrk.com/pH.htmlhttp://www.johnkyrk.com/pH.htmlhttp://www.johnkyrk.com/pH.htmlhttp://www.johnkyrk.com/pH.html

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     pH Concentrations

    What type o# a solution has a pH o#

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    =ndicators

    >indicate the concentration o# a substance by color.

    @ni"ersal indicator is only one e5ample.

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    http811.bg#l.org1bg#l1custom1r 

    esourcesA#tp1clientA#tp1/s31scien

    ce1acids1inde5.htm *ead the >Help section to re"ie

    Chose >itmus *eactions

    %ype your @ name

    ollo directions

    http://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htmhttp://www.bgfl.org/bgfl/custom/resources_ftp/client_ftp/ks3/science/acids/index.htm

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    *eaction o# Darious Materials to

     pH & itmus 0apersMaterial%ested

    *eaction to*ed itmus

    *eaction toBlue itmus

     pH accordingto pH paper 

    HCl

     Ea+H

    H2+

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    +ther ays o# measuring pH

     pH meter 

     (  Hand6held de"ice

     pH probe

     (  @ses a computer

    inter#ace

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     pH ab

    Fou ill be using atechni;ue called titration

    'n acid or base ill be

     placed in a buret  andsloly added to the testsolution (  Water 

     (  Bu##er

     (  Cell homogenate

    %he computer ill assist inrecording any changes in pH

    'cid 

    or

     base

    %est soln.

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    Hypotheses

    'n assumption subjectto verification or

     proof.

    Written in the “If…then…” #ormat.

    !5ample8 (  =# acid is added to

    ater$ then the pHillAAAAA 

     (  =# base is added toater$ then the pHillAAAAA 

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    Chemical Bu##ers

    Chemical substances thatneutralize small amountsor either acid or base

    added to a solution B@!* )+ E+%

     E!C!'*=F E!@%*'=! %H!+@%=+E %+ ' 0H 9I

    !58 stomach acid remainsat a pH o# 2 regardless o#hether you ingest acidicor basic substances

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    'pplication o# Bu##ers

    Chemicalreactions illonly occurnormally in asystem thatresists a changein pH

    %his is part o# a process /nonas homeostasis

    %he pH o# many li"ing things tends to be around neutral.

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    Biochemistry

    %he chemistry o# biological substances and processes.

    =n"ol"es carbon compounds (  +rganic

    Carbon6based and originated #rom a li"ing thing !58 proteins$ lipids$ carbohydrates$ and nucleic acids

     (  =norganic >not organic

    !58 ater 

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    Monomer "s. 0olymer 

    >Mono J >-

    ' monomer is the

     basic building bloc/ 

    >poly J >many

    ' polymer is made up

    o# many monomers

    Ho do the 2

    >bo5cars :oin

    together to #orm

    a long train?

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    More analogies?

    •  

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    )ehydration ynthesis or

    Condensation *eaction

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    Condensation1Hydrolysis

    )emonstration http811.t"dsb.on.ca1estmin1science1sb

    ioac1biochem1condense.htm

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htm

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     Eote8 Glucose and #ructose are isomers

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    Hydrolysis

    Molecules ill not only need to be built$ asin the case o# ma/ing ne muscle and bone$

     but they ill also need to be bro/en don$

    as in the case o# digestion o# #ood. %his time$ ater must be added among

    enzymes4 to brea/ the bonds.

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    !5ample8

    Ma/ing ne

    muscle #or

    groth in your

     body

    !5ample8

    )igesting muscle

    a#ter eating meat

    in order to get the

    monomers to

    ma/e ne muscle

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    *e"ie

    Monosaccharide K2Monosaccharide K-

    )isaccharide

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    *e"ie o# chemical reactions

    http811.isc6online.com1ob:ects1inde5

     At:.asp?ob:=)J'0-37

    http://www.wisc-online.com/objects/index_tj.asp?objID=AP13004http://www.wisc-online.com/objects/index_tj.asp?objID=AP13004http://www.wisc-online.com/objects/index_tj.asp?objID=AP13004http://www.wisc-online.com/objects/index_tj.asp?objID=AP13004

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    CarbohydratesType ofCompound

    Examples Elements Subunit(monomer)

    Functions

    onosaccharide Glucose$#ructose$galactose

    CLH-2+L

    Carbon$ hydrogen$o5ygen

    !5actly a-C82H8-+

    itsel# ource o# energy7Cal1g4

    !isaccharide ucrose$maltose$

    actose

    C-2H22+--

    C$ H$ + 'ppro5.a -C82H8-+

    Mono6saccharide

    ource o# energy7Cal1g4

    "olysaccharide Glycogen$

    starch$

    cellulose

    C$ H$ + 'ppro5.a -C82H8-+ Mono6saccharide tored energy inanimals

    tored energy in plants

    tructural componento# plant cell alls

    http://www.ilexikon.com/images/6/69/Glukose-Ring.png

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    *ecall

    Monomer monomer J polymer H2+

    %his is called

    )ehydration synthesis or condensation

    !5ample8

    CLH-2+L  CLH-2+L J C-2H22+-- H2+

    Fou try8

    3CLH-2+L4 J C-NH32+-L  2H2+

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    ormation o# a polysaccharide

    http811science.nhmccd.edu1biol1dehydrat1deh

    ydrat.html

    http811.t"dsb.on.ca1estmin1science1sbioac1biochem1condense.htm

    i id

    http://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/condense.htmhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.htmlhttp://science.nhmccd.edu/biol/dehydrat/dehydrat.html

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    ipids

    Type of

    Compound

    Examples Elements Subunit

    (monomer)

    Functions

    Tri#lycerides ats$

    +ils

    Carbon$hydrogen$o5ygen

    3 #atty acids and aglycerol

    tored energy,Cal1g4$ insulation$ner"e impulses$ protection

    econdary sol"ent o#

    cell

    $axes !ar a5 ame - #atty acid andalcohol chain

    0rotection$aterproo#ing

    Steroids Hormones$

    cholesterol

    ame used carbon rings *egulate chemical

    reactions

    "hospholipids Cellmembranes

    same 2 #atty acids and aglycerol

    *egulates hat entersand lea"es a cell

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    ormation o# a %riglyceride

    http811.t"dsb.on.ca1estmin1science1sbi

    oac1biochem1triglyc.htm

    http://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htmhttp://www.tvdsb.on.ca/westmin/science/sbioac/biochem/triglyc.htm

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    Why cholesterol is good and

     bad4 http811.iley.com1legacy1college1boyer1

    7939,1animations1animations.htm

    0 t i

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    0roteinsType ofCompound

    Examples Elements Subunit(monomer)

    Functions

    Hemoglobin

    Carbon$hydrogen$o5ygen$nitrogen

    'mino acid General #unction o# a protein is building andrepair. (May be used asan energy source as alast resort  7Cal1g4?

    Binds gases in red blood cells

    =nsulin ame ame *egulates blood sugarle"els

    'lbumin ame ame Eourishing componento# egg hites

    Oeratin ame ame tructural componento# hair$ s/in$ and nails

    !nzymes ame ame 'ct as a catalyst byregulating chemical

    reaction rates

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    ormation o# a polypeptide

    http811.t"dsb.on.ca1estmin1science1sbi

    oac1biochem1amino.htm

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    !nzymes

    Most enzyme are proteins

    %hree characteristics ( *eusable

     ( peci#ic

     ( Catalyst loer the acti"ation energy !a4o# a

    reaction4 ( http8113.#hs.usyd.edu.au1bio1homeostasis1C

    ontrolAystems.htm read #rom the introductionto the de#inition o# homeostasis4

    http811 mhhe com1physsci1ch

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    http811.mhhe.com1physsci1chemistry1essentialchemistry1#lash1

    acti"a2.s#  hort "ideo clip o# e5othermic reactions.

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    2H2+2 → 2H2+ +2 

    catalase

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    Catalase

    'n enzyme #ound in any

    li"ing tissue$ plant or

    animal

    Catalase or/s best under

    constant conditions

    homeostasis4 o#

    temperature and pH

    0redict hat the graph

    ould loo/ li/e i# the

    li"er$ containing catalase$is

     (  Boiled

     (  'cidi#ied

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    What happened?

    %he enzyme catalase as denatured E+%/illed4.

    ince enzymes are speci#ic$ catalase no

    longer >#it the substrate.

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    Type ofcompound

    Examples Elements Subunits(monomers)

    Functions

    %ucleic &cids )E'

    *E'

    Carbon$hydrogen$o5ygen$nitrogen$ phosphorus

     Eucleotide tores geneticin#ormation #orma/ing proteins

    )irectlyin"ol"ed in proteinsynthesis

    $ater =ce$ li;uid

    ater$"apor 

    Hydrogen$

    o5ygen

    H2+ 0rimary sol"ent

    o# the cell6polar 

    6cohesi"e

    6adhesi"e

    http811programs northlandcollege

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    http811programs.northlandcollege.edu1biology1Biology----1animati

    ons1hydrogenbonds.html hort "ideo clip about aterPs polarity and

    hydrogen bonding properties.

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     Eice ;uiz re"ieing the Big 7

    Molecules http811science.nhmccd.edu1biol1macmole.ht

    ml