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PowerPoint Lectures Campbell Biology: Concepts & Connections, 8th Edition, Global Edition REECE • TAYLOR • SIMON • DICKEY • HOGAN Lecture by Edward J. Zalisko Chapter 4 Tour of the Cell © 2016 Pearson Education, Ltd.

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Page 1: 04 lecture presentation

copy 2016 Pearson Education Ltd

PowerPoint LecturesCampbell Biology Concepts amp Connections 8th Edition Global EditionREECE bull TAYLOR bull SIMON bull DICKEY bull HOGAN

Lecture by Edward J Zalisko

Chapter 4 A Tour of the Cell

copy 2016 Pearson Education Ltd

Introduction

bull Cells have a cytoskeleton thatbull provides support andbull allows some cells to crawl and others to swim

bull Our understanding of nature often goes hand in hand with the invention and refinement of instruments that extend our senses

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Introduction

bull In 1665 Hooke examined a piece of cork under a crude microscope and identified ldquolittle roomsrdquo as cells

bull Leeuwenhoek working at about the same time used more refined lenses to describe living cells from blood sperm and pond water

bull Since the days of Hooke and Leeuwenhoek improved microscopes have vastly expanded our view of the cell

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Figure 40-1

copy 2016 Pearson Education Ltd

Figure 40-2

Introduction to the Cell

Chapter 4 Big Ideas

The Nucleus andRibosomes

The EndomembraneSystem

Energy-ConvertingOrganelles

The Cytoskeleton andCell Surfaces

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INTRODUCTION TO THE CELL

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41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

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41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

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41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

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41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

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Figure 41a

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Figure 41b

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Figure 41c

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Figure 41d

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Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

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Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

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Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

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Figure 4UN01

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

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Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

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Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

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Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

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Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

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You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 2: 04 lecture presentation

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Introduction

bull Cells have a cytoskeleton thatbull provides support andbull allows some cells to crawl and others to swim

bull Our understanding of nature often goes hand in hand with the invention and refinement of instruments that extend our senses

copy 2016 Pearson Education Ltd

Introduction

bull In 1665 Hooke examined a piece of cork under a crude microscope and identified ldquolittle roomsrdquo as cells

bull Leeuwenhoek working at about the same time used more refined lenses to describe living cells from blood sperm and pond water

bull Since the days of Hooke and Leeuwenhoek improved microscopes have vastly expanded our view of the cell

copy 2016 Pearson Education Ltd

Figure 40-1

copy 2016 Pearson Education Ltd

Figure 40-2

Introduction to the Cell

Chapter 4 Big Ideas

The Nucleus andRibosomes

The EndomembraneSystem

Energy-ConvertingOrganelles

The Cytoskeleton andCell Surfaces

copy 2016 Pearson Education Ltd

INTRODUCTION TO THE CELL

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41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

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41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

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Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 3: 04 lecture presentation

copy 2016 Pearson Education Ltd

Introduction

bull In 1665 Hooke examined a piece of cork under a crude microscope and identified ldquolittle roomsrdquo as cells

bull Leeuwenhoek working at about the same time used more refined lenses to describe living cells from blood sperm and pond water

bull Since the days of Hooke and Leeuwenhoek improved microscopes have vastly expanded our view of the cell

copy 2016 Pearson Education Ltd

Figure 40-1

copy 2016 Pearson Education Ltd

Figure 40-2

Introduction to the Cell

Chapter 4 Big Ideas

The Nucleus andRibosomes

The EndomembraneSystem

Energy-ConvertingOrganelles

The Cytoskeleton andCell Surfaces

copy 2016 Pearson Education Ltd

INTRODUCTION TO THE CELL

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

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41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

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Figure 41a

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Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

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Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

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Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

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You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

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You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 4: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 40-1

copy 2016 Pearson Education Ltd

Figure 40-2

Introduction to the Cell

Chapter 4 Big Ideas

The Nucleus andRibosomes

The EndomembraneSystem

Energy-ConvertingOrganelles

The Cytoskeleton andCell Surfaces

copy 2016 Pearson Education Ltd

INTRODUCTION TO THE CELL

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41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

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41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

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Figure 41a

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Figure 41b

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Figure 41c

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Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

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Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

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Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

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Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

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Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 5: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 40-2

Introduction to the Cell

Chapter 4 Big Ideas

The Nucleus andRibosomes

The EndomembraneSystem

Energy-ConvertingOrganelles

The Cytoskeleton andCell Surfaces

copy 2016 Pearson Education Ltd

INTRODUCTION TO THE CELL

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41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

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41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

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Figure 41a

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Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 6: 04 lecture presentation

copy 2016 Pearson Education Ltd

INTRODUCTION TO THE CELL

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

copy 2016 Pearson Education Ltd

Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 7: 04 lecture presentation

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull A variety of microscopes have been developed for a clearer view of cells and cellular structure

bull The first microscopes were light microscopes In a light microscope (LM) visible light passes through a specimen then through glass lenses and finally is projected into the viewerrsquos eye

bull Specimens can be magnified by up to 1000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

copy 2016 Pearson Education Ltd

Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 8: 04 lecture presentation

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Magnification is the increase in an objectrsquos image size compared with its actual size

bull Resolution is a measure of the clarity of an image In other words it is the ability of an instrument to show two nearby objects as separate

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41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

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41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

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Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 9: 04 lecture presentation

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Microscopes have limitationsbull The human eye and the microscope have limits of

resolutionmdashthe ability to distinguish between small structures

bull Therefore the light microscope cannot provide the details of a small cellrsquos structure

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

copy 2016 Pearson Education Ltd

Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

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Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

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Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

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Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 10: 04 lecture presentation

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Using light microscopes scientists studiedbull microorganismsbull animal and plant cells andbull some structures within cells

bull In the 1800s these studies led to cell theory which states that

bull all living things are composed of cells andbull all cells come from other cells

copy 2016 Pearson Education Ltd

Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

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You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 11: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41a

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

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You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 12: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41b

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

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Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

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You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 13: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41c

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

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41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

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Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

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Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

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Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

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Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

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Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

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You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 14: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41d

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 15: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41e-0

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Una

ided

eye

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

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Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 16: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41e-1

Human heightLength of somenerve and muscle cells

Chicken egg

Frog egg

ParameciumHuman eggU

naid

ed e

ye

10 m

1 m

100 mm(10 cm)

10 mm(1 cm)

1 mm

100 μm

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 17: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 41e-2

Frog egg

ParameciumHuman egg

Most plant andanimal cellsNucleusMost bacteriaMitochondrion

Smallest bacteriaViruses

Ribosome

ProteinsLipids

SmallmoleculesAtoms

Ligh

t mic

rosc

ope

Elec

tron

mic

rosc

ope

1 mm

100 nm

10 nm

1 nm

01 nm

100 μm

10 μm

1 μm

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 18: 04 lecture presentation

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Beginning in the 1950s scientists started using a very powerful microscope called the electron microscope (EM) to view the ultrastructure of cells

bull Instead of light EM uses a beam of electronsbull Electron microscopes can

bull resolve biological structures as small as 2 nanometers and

bull magnify up to 100000 times

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 19: 04 lecture presentation

copy 2016 Pearson Education Ltd

41 Microscopes reveal the world of the cell

bull Scanning electron microscopes (SEMs) study the detailed architecture of cell surfaces

bull Transmission electron microscopes (TEMs) study the details of internal cell structure

bull Differential interference light microscopes amplify differences in density so that structures in living cells appear almost three-dimensional

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 20: 04 lecture presentation

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Cell size mustbull be large enough to house DNA proteins and

structures needed to survive and reproduce butbull remain small enough to allow for a surface-to-

volume ratio that will allow adequate exchange with the environment

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

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Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 21: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 42a

Total volume

3

3

1

1

2 6

Total surfaceareaSurface-to-volume ratio

27 units3 27 units3

54 units2 162 units2

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

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Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 22: 04 lecture presentation

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull The plasma membrane forms a flexible boundary between the living cell and its surroundings

bull Phospholipids form a two-layer sheet called a phospholipid bilayer in which

bull hydrophilic heads face outward exposed to water and

bull hydrophobic tails point inward shielded from water

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42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

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Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 23: 04 lecture presentation

copy 2016 Pearson Education Ltd

42 The small size of cells relates to the need to exchange materials across the plasma membrane

bull Membrane proteins are embedded in the lipid bilayer

bull Some proteins form channels (tunnels) that shield ions and other hydrophilic molecules as they pass through the hydrophobic center of the membrane

bull Other proteins serve as pumps using energy to actively transport molecules into or out of the cell

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 24: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 42b

Outside cell

Inside cell

HydrophilicheadsHydrophobictails

Phospholipid

Channelprotein

Hydrophilicregions ofa protein

Hydrophobicregions ofa protein

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 25: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 4UN01

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

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Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 26: 04 lecture presentation

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Bacteria and archaea are prokaryotic cellsbull All other forms of life are composed of eukaryotic

cellsbull Eukaryotic cells are distinguished by having

bull a membrane-enclosed nucleus andbull many membrane-enclosed organelles that perform

specific functionsbull Prokaryotic cells are smaller and simpler in

structure

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

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Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

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Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

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Figure 43-2

A colorized TEM of thebacterium Escherichia coli

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44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 27: 04 lecture presentation

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Prokaryotic and eukaryotic cells havebull a plasma membranebull an interior filled with a thick jellylike fluid called the

cytosol bull one or more chromosomes which carry genes

made of DNA andbull ribosomes tiny structures that make proteins

according to instructions from the genes

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

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43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

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Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 28: 04 lecture presentation

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull The inside of both types of cells is called the cytoplasm

bull However in eukaryotic cells this term refers only to the region between the nucleus and the plasma membrane

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

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Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 29: 04 lecture presentation

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull In a prokaryotic cellbull the DNA is coiled into a region called the nucleoid

(nucleus-like) andbull no membrane surrounds the DNA

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

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Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 30: 04 lecture presentation

copy 2016 Pearson Education Ltd

43 Prokaryotic cells are structurally simpler than eukaryotic cells

bull Outside the plasma membrane of most prokaryotes is a fairly rigid chemically complex cell wall which

bull protects the cell andbull helps maintain its shape

bull Some prokaryotes have surface projectionsbull Short projections help attach prokaryotes to each

other or their substratebull Longer projections called flagella (singular flagellum) propel a prokaryotic cell through its liquid environment

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

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Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

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Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

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Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

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Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

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Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

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Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 31: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 43-0

Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium

A colorized TEM of thebacterium Escherichia coli

Flagella

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

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Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

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You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 32: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 43-1Fimbriae

Ribosomes

Nucleoid

PlasmamembraneCell wall

CapsuleBacterialchromosome

A typical rod-shapedbacterium Flagella

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

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Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 33: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 43-2

A colorized TEM of thebacterium Escherichia coli

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

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44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

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418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

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Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

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421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

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Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

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You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

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You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 34: 04 lecture presentation

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull A eukaryotic cell containsbull a membrane-enclosed nucleus andbull various other organelles (ldquolittle organsrdquo) which

perform specific functions in the cell

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

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You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 35: 04 lecture presentation

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The structures and organelles of eukaryotic cells perform four basic functions

1 The nucleus and ribosomes are involved in the genetic control of the cell

2 The endoplasmic reticulum Golgi apparatus lysosomes vacuoles and peroxisomes are involved in the manufacture distribution and breakdown of molecules

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44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 36: 04 lecture presentation

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

3 Mitochondria in all cells and chloroplasts in plant cells are involved in energy processing

4 Structural support movement and communication between cells are functions of the cytoskeleton plasma membrane and cell wall

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44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 37: 04 lecture presentation

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull The internal membranes of eukaryotic cells partition it into compartments

bull Cellular metabolism the many chemical activities of cells occurs within organelles

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44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

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44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

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46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

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47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

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Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

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Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 38: 04 lecture presentation

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Almost all of the organelles and other structures of animals cells are present in plant cells

bull A few exceptions existbull Lysosomes and centrosomes containing centrioles

are not found in plant cellsbull Only the sperm cells of a few plant species have

flagella

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 39: 04 lecture presentation

copy 2016 Pearson Education Ltd

44 Eukaryotic cells are partitioned into functional compartments

bull Plant but not animal cells havebull a rigid cell wall that contains cellulosebull plasmodesmata cytoplasmic channels through cell

walls that connect adjacent cellsbull chloroplasts where photosynthesis occurs andbull a central vacuole a compartment that stores water

and a variety of chemicals

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

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THE NUCLEUS AND RIBOSOMES

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

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45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

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Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

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46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

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Video Chlamydomonas

>

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Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

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Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

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Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

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419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

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Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 40: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 44a

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

Golgi apparatus

LysosomeMitochondrion

Centrosomewith pair ofcentrioles

Plasmamembrane

Peroxisome

Intermediatefilament

MicrofilamentMicrotubule

CYTOSKELETON

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

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Animation Gap Junctions

>

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Animation Tight Junctions

>

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Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

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Table 4-22-0

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Table 4-22-1

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Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

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Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 41: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 44b

Roughendoplasmicreticulum

Smoothendoplasmicreticulum

NUCLEUSNuclear envelopeNucleolusChromatin

Ribosomes

Plasmamembrane

Peroxisome

Mitochondrion

MicrofilamentMicrotubule

CYTOSKELETON

Cell wall ofadjacent cell Golgi

apparatus

PlasmodesmaCell wall

Chloroplast

Centralvacuole

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 42: 04 lecture presentation

copy 2016 Pearson Education Ltd

THE NUCLEUS AND RIBOSOMES

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 43: 04 lecture presentation

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleusbull contains most of the cellrsquos DNA andbull controls the cellrsquos activities by directing protein

synthesis by making messenger RNA (mRNA)

bull DNA is associated with many proteins and is organized into structures called chromosomes

bull When a cell is not dividing this complex of proteins and DNA called chromatin appears as a diffuse mass within the nucleus

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 44: 04 lecture presentation

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The double membrane nuclear envelope has pores that

bull regulate the entry and exit of large molecules and bull connect with the cellrsquos network of membranes

called the endoplasmic reticulum

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45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

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Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

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THE ENDOMEMBRANE SYSTEM

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47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

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47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 45: 04 lecture presentation

copy 2016 Pearson Education Ltd

45 The nucleus contains the cellrsquos genetic instructions

bull The nucleolus isbull a prominent structure in the nucleus andbull the site of ribosomal RNA (rRNA) synthesis

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 46: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 45

NucleolusNuclearenvelope

Endoplasmicreticulum

Ribosome

Pore Chromatin

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 47: 04 lecture presentation

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Ribosomes are involved in the cellrsquos protein synthesis

bull Ribosomes are the cellular components that use instructions from the nucleus written in mRNA to build proteins

bull Cells that make a lot of proteins have a large number of ribosomes

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 48: 04 lecture presentation

copy 2016 Pearson Education Ltd

46 Ribosomes make proteins for use in the cell and export

bull Some ribosomes are free ribosomes others are bound

bull Free ribosomes are suspended in the cytosolbull Bound ribosomes are attached to the outside of the

endoplasmic reticulum or nuclear envelope

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 49: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 46

Rough ER

Bound ribosomeEndoplasmicreticulum

Protein

Ribosome

Free ribosomemRNA

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 50: 04 lecture presentation

copy 2016 Pearson Education Ltd

THE ENDOMEMBRANE SYSTEM

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 51: 04 lecture presentation

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of the membranes within a eukaryotic cell are part of the endomembrane system

bull Some of these membranes are physically connected and others are linked when tiny vesicles (sacs made of membrane) transfer membrane segments between them

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 52: 04 lecture presentation

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull Many of these organelles interact in thebull synthesisbull distributionbull storage andbull export of molecules

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

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Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 53: 04 lecture presentation

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The endomembrane system includes thebull nuclear envelopebull endoplasmic reticulum (ER)bull Golgi apparatusbull lysosomesbull vacuoles andbull plasma membrane

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47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

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48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

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Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

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48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

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49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

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49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

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410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

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Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

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Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

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Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

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Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

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Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

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411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

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Video Paramecium Vacuole

>

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Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

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412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

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Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

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412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

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ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

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413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

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413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

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Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

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414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

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414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

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Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

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Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

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Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

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THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

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Video Cytoplasmic Streaming

>

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

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Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

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Figure 416-1

Nucleus

Microtubule

25 nm

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Figure 416-2

Nucleus

Intermediate filament

10 nm

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Figure 416-3

Microfilament

7 nm

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Figure 416-4

Nucleus

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Figure 416-5

Nucleus

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Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

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417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

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Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

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418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

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419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

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420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

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422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 54: 04 lecture presentation

copy 2016 Pearson Education Ltd

47 Many organelles are connected in the endomembrane system

bull The largest component of the endomembrane system is the endoplasmic reticulum (ER) an extensive network of flattened sacs and tubules

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 55: 04 lecture presentation

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull There are two kinds of endoplasmic reticulum which differ in structure and function

1 Smooth ER lacks attached ribosomes2 Rough ER has bound ribosomes that stud the

outer surface of the membrane

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 56: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 48a

Rough ER

Smooth ER

Ribosomes

Rough ERSmooth ER

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 57: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 48b

mRNA

1

2

3

4

Bound ribosome

Transport vesiclebuds off

Secretoryproteininside trans-port vesicle

Sugar chain

Rough ER

GlycoproteinGrowingpolypeptide

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 58: 04 lecture presentation

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Smooth ER is involved in a variety of metabolic processes including

bull the production of enzymes important in the synthesis of lipids oils phospholipids and steroids

bull the production of enzymes that help process drugs alcohol and other potentially harmful substances and

bull the storage of calcium ions

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 59: 04 lecture presentation

copy 2016 Pearson Education Ltd

48 The endoplasmic reticulum is a biosynthetic workshop

bull Rough ER makesbull additional membrane for itself andbull secretory proteins

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 60: 04 lecture presentation

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull The Golgi apparatus serves as a molecular warehouse and processing station for products manufactured by the ER

bull Products travel in transport vesicles from the ER to the Golgi apparatus

bull One side of the Golgi stack serves as a receiving dock for transport vesicles produced by the ER

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

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415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 61: 04 lecture presentation

copy 2016 Pearson Education Ltd

49 The Golgi apparatus modifies sorts and ships cell products

bull Products of the ER are modified as a Golgi sac progresses through the stack

bull The ldquoshippingrdquo side of the Golgi functions as a depot where products in vesicles bud off and travel to other sites

copy 2012 Pearson Education Inc

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 62: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 49

Golgi apparatus

1

2

3

4

ldquoReceivingrdquo side of Golgi apparatusTransport vesiclefrom the ER

Transportvesicle fromthe Golgi

ldquoShippingrdquo side of Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 63: 04 lecture presentation

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull A lysosome is a membrane-enclosed sac of digestive enzymes

bull made by rough ER andbull processed in the Golgi apparatus

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 64: 04 lecture presentation

copy 2016 Pearson Education Ltd

410 Lysosomes are digestive compartments within a cell

bull Lysosomesbull fuse with food vacuoles and digest foodbull destroy bacteria engulfed by white blood cells orbull fuse with other vesicles containing damaged

organelles or other materials to be recycled within a cell

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

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Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 65: 04 lecture presentation

copy 2016 Pearson Education Ltd

Animation Lysosome Formation

>

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 66: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410a-1

Digestiveenzymes

Lysosome

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 67: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410a-2

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

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416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

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418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 68: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410a-3

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 69: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410a-4

Digestiveenzymes

Lysosome

Food vacuole

Plasma membrane

Digestion

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

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413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 70: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410b-1

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 71: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410b-2

Lysosome

Vesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 72: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 410b-3

Lysosome

DigestionVesicle containingdamaged mitochondrion

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 73: 04 lecture presentation

copy 2016 Pearson Education Ltd

411 Vacuoles function in the general maintenance of the cell

bull Vacuoles are large vesicles that have a variety of functions

bull Some protists have contractile vacuoles which help to eliminate water from the protist

bull In plants vacuoles maybull have digestive functionsbull contain pigments orbull contain poisons that protect the plant

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 74: 04 lecture presentation

copy 2016 Pearson Education Ltd

Video Paramecium Vacuole

>

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 75: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 411a

Contractilevacuoles

Nucleus

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 76: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 411b

Central vacuole

Chloroplast

Nucleus

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 77: 04 lecture presentation

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull The following figure summarizes the relationships among the major organelles of the endomembrane system

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 78: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 412

Nucleus

Smooth ER

Rough ER

Transport vesicle

Lysosome

Nuclear envelope

Golgi apparatus

Plasmamembrane

Transportvesicle

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 79: 04 lecture presentation

copy 2016 Pearson Education Ltd

412 A review of the structures involved in manufacturing and breakdown

bull Peroxisomes are metabolic compartments that do not originate from the endomembrane system

bull How they are related to other organelles is still unknown

bull Some peroxisomes break down fatty acids to be used as cellular fuel

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 80: 04 lecture presentation

copy 2016 Pearson Education Ltd

ENERGY-CONVERTING ORGANELLES

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 81: 04 lecture presentation

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria are organelles that carry out cellular respiration in nearly all eukaryotic cells

bull Cellular respiration converts the chemical energy in foods to chemical energy in ATP (adenosine triphosphate)

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 82: 04 lecture presentation

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Mitochondria have two internal compartments1 The intermembrane space is the narrow region

between the inner and outer membranes2 The mitochondrial matrix contains

bull the mitochondrial DNAbull ribosomes andbull many enzymes that catalyze some of the reactions

of cellular respiration

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 83: 04 lecture presentation

copy 2016 Pearson Education Ltd

413 Mitochondria harvest chemical energy from food

bull Folds of the inner mitochondrial membrane called cristae increase the membranersquos surface area enhancing the mitochondrionrsquos ability to produce ATP

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 84: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 413

Mitochondrion

Intermembranespace

Outermembrane

Innermembrane

CristaMatrix

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 85: 04 lecture presentation

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Photosynthesis is the conversion of light energy from the sun to the chemical energy of sugar molecules

bull Chloroplasts are the photosynthesizing organelles of plants and algae

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 86: 04 lecture presentation

copy 2016 Pearson Education Ltd

414 Chloroplasts convert solar energy to chemical energy

bull Chloroplasts are partitioned into compartmentsbull Between the outer and inner membrane is a thin

intermembrane spacebull Inside the inner membrane is a thick fluid called

stroma which contains the chloroplast DNA ribosomes many enzymes and a network of interconnected sacs called thylakoids where green chlorophyll molecules trap solar energy

bull In some regions thylakoids are stacked like poker chips Each stack is called a granum

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 87: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 414

Chloroplast

Granum

Stroma

Inner andouter membranes

Thylakoid

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 88: 04 lecture presentation

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull Mitochondria and chloroplasts containbull DNA andbull ribosomes

bull The structure of this DNA and these ribosomes is very similar to that found in prokaryotic cells

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 89: 04 lecture presentation

copy 2016 Pearson Education Ltd

415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolved by endosymbiosis

bull The endosymbiont theory states thatbull mitochondria and chloroplasts were formerly small

prokaryotes andbull they began living within larger cells

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 90: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 415Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 91: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 415-1Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 92: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 415-2Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Nonphotosynthetic eukaryote

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 93: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 415-3Endoplasmicreticulum

Nucleus

Ancestor ofeukaryotic cells (host cell)

Mitochondrion

Engulfing ofphotosyntheticprokaryote

Mitochondrion

Photosynthetic eukaryote

Chloroplast

Nonphotosynthetic eukaryote

At leastone cell

Engulfing of oxygen-using prokaryote

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 94: 04 lecture presentation

copy 2016 Pearson Education Ltd

THE CYTOSKELETON ANDCELL SURFACES

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 95: 04 lecture presentation

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Cells contain a network of protein fibers called the cytoskeleton which organize the structures and activities of the cell

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 96: 04 lecture presentation

copy 2016 Pearson Education Ltd

Video Cytoplasmic Streaming

>

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 97: 04 lecture presentation

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microtubules (made of tubulin)bull shape and support the cell andbull act as tracks along which organelles equipped with

motor proteins move

bull In animal cells microtubules grow out from a region near the nucleus called the centrosome which contains a pair of centrioles each composed of a ring of microtubules

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 98: 04 lecture presentation

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Intermediate filamentsbull are found in the cells of most animalsbull reinforce cell shape and anchor some organelles

andbull are often more permanent fixtures in the cell

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 99: 04 lecture presentation

copy 2016 Pearson Education Ltd

416 The cellrsquos internal skeleton helps organize its structure and activities

bull Microfilaments (actin filaments)bull support the cellrsquos shape andbull are involved in motility

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 100: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-0

Nucleus

Nucleus

Microtubule

25 nmIntermediate filament

10 nm

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 101: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-1

Nucleus

Microtubule

25 nm

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 102: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-2

Nucleus

Intermediate filament

10 nm

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 103: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-3

Microfilament

7 nm

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 104: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-4

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 105: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-5

Nucleus

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 106: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 416-6

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 107: 04 lecture presentation

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1940s biochemists first isolated and identified the proteins actin and myosin from muscle cells

bull In 1954 scientists using newly developed techniques of microscopy established how filaments of actin and myosin interact in muscle contraction

bull In the next decade researchers identified actin filaments in all types of cells

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 108: 04 lecture presentation

copy 2016 Pearson Education Ltd

417 SCIENTIFIC THINKING Scientists discovered the cytoskeleton using the tools of biochemistry and microscopy

bull In the 1970s scientists were able to visualize actin filaments using fluorescent tags and in living cells

bull In the 1980s biologists were able to record the changing architecture of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 109: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 417

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 110: 04 lecture presentation

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull The short numerous appendages that propel protists such as Paramecium are called cilia (singular cilium)

bull Other protists may move using flagella which are longer than cilia and usually limited to one or a few per cell

bull Some cells of multicellular organisms also have cilia or flagella

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 111: 04 lecture presentation

copy 2016 Pearson Education Ltd

Video Paramecium Cilia

>

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 112: 04 lecture presentation

copy 2016 Pearson Education Ltd

Video Chlamydomonas

>

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 113: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 418a

Cilia

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 114: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 418b

Flagellum

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 115: 04 lecture presentation

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull A flagellum longer than cilia propels a cell by an undulating whiplike motion

bull Cilia work more like the oars of a boatbull Although differences exist flagella and cilia have a

common structure and mechanism of movement

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 116: 04 lecture presentation

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Both flagella and cilia are composed of microtubules wrapped in an extension of the plasma membrane

bull In nearly all eukaryotic cilia and flagella a ring of nine microtubule doublets surrounds a central pair of microtubules

bull This arrangement is called the 9 2 patternbull The microtubule assembly is anchored in a basal

body with nine microtubule triplets arranged in a ring

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 117: 04 lecture presentation

copy 2016 Pearson Education Ltd

Animation Cilia and Flagella

>

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 118: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 418c-0

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 119: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 418c-1

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 120: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 418c-2

Outermicrotubuledoublet

Central microtubules

Cross-linkingproteinsMotor proteins(dyneins)

Plasma membrane

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 121: 04 lecture presentation

copy 2016 Pearson Education Ltd

418 Cilia and flagella move when microtubules bend

bull Cilia and flagella move by bending motor proteins called dynein feet

bull These feet attach to and exert a sliding force on an adjacent doublet

bull This ldquowalkingrdquo causes the microtubules to bend

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 122: 04 lecture presentation

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull Animal cells synthesize and secrete an elaborate extracellular matrix (ECM) which

bull helps hold cells together in tissues andbull protects and supports the plasma membrane

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 123: 04 lecture presentation

copy 2016 Pearson Education Ltd

419 The extracellular matrix of animal cells functions in support and regulation

bull The ECM may attach to the cell through other glycoproteins that then bind to membrane proteins called integrins

bull Integrinsbull span the membrane andbull attach on the other side to proteins connected to

microfilaments of the cytoskeleton

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 124: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 419

Collagen fiber

EXTRACELLULAR FLUID

CYTOPLASM

Glycoproteincomplex with longpolysaccharide

Connectingglycoprotein

Integrin

Plasmamembrane

Microfilamentsof cytoskeleton

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 125: 04 lecture presentation

copy 2016 Pearson Education Ltd

420 Three types of cell junctions are found in animal tissues

bull Adjacent cells adhere interact and communicate through specialized junctions between them

bull Tight junctions prevent leakage of fluid across a layer of epithelial cells

bull Anchoring junctions fasten cells together into sheets

bull Gap junctions are channels that allow small molecules to flow through protein-lined pores between cells

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 126: 04 lecture presentation

copy 2016 Pearson Education Ltd

Animation Desmosomes

>

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 127: 04 lecture presentation

copy 2016 Pearson Education Ltd

Animation Gap Junctions

>

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 128: 04 lecture presentation

copy 2016 Pearson Education Ltd

Animation Tight Junctions

>

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 129: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 420

Tight junction

Anchoringjunction

Gap junction

Plasma membranesof adjacent cells

Ions or small molecules Extracellular matrix

Tight junctionsprevent fluid frommoving across alayer of cells

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 130: 04 lecture presentation

copy 2016 Pearson Education Ltd

421 Cell walls enclose and support plant cells

bull A plant cell but not an animal cell has a rigid cell wall that

bull protects and provides skeletal support that helps keep the plant upright and

bull is primarily composed of cellulose

bull Plant cells have cell junctions called plasmodesmata that allow plants tissues to share

bull waterbull nourishment andbull chemical messages

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 131: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 421

Vacuole

Plant cellwalls

Plasmodesmata

Primary cell wallSecondary cell wallPlasma membrane

Cytosol

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 132: 04 lecture presentation

copy 2016 Pearson Education Ltd

422 Review Eukaryotic cell structures can be grouped on the basis of four main functions

bull Eukaryotic cell structures can be grouped on the basis of four functions

1 genetic control2 manufacturing distribution and breakdown of

materials3 energy processing and4 structural support movement and intercellular

communication

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 133: 04 lecture presentation

copy 2016 Pearson Education Ltd

Table 4-22-0

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 134: 04 lecture presentation

copy 2016 Pearson Education Ltd

Table 4-22-1

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 135: 04 lecture presentation

copy 2016 Pearson Education Ltd

Table 4-22-2

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 136: 04 lecture presentation

copy 2016 Pearson Education Ltd

You should now be able to

1 Describe the importance of microscopes in understanding cell structure and function

2 Describe the two parts of cell theory3 Distinguish between the structures of prokaryotic

and eukaryotic cells4 Explain how cell size is limited5 Describe the structure and functions of cell

membranes

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 137: 04 lecture presentation

copy 2016 Pearson Education Ltd

You should now be able to

6 Explain why compartmentalization is important in eukaryotic cells

7 Compare the structures of plant and animal cells Note the function of each cell part

8 Compare the structures and functions of chloroplasts and mitochondria

9 Describe the evidence that suggests that mitochondria and chloroplasts evolved by endosymbiosis

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 138: 04 lecture presentation

copy 2016 Pearson Education Ltd

You should now be able to

10 Compare the structures and functions of microfilaments intermediate filaments and microtubules

11 Relate the structure of cilia and flagella to their functions

12 Relate the structure of the extracellular matrix to its functions

13 Compare the structures and functions of tight junctions anchoring junctions and gap junctions

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 139: 04 lecture presentation

copy 2016 Pearson Education Ltd

You should now be able to

14 Relate the structures of plant cell walls and plasmodesmata to their functions

15 Describe the four functional categories of organelles in eukaryotic cells

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 140: 04 lecture presentation

copy 2016 Pearson Education Ltd

Table 4-1

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 141: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 4UN02

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 142: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 4UN03

a bc

d

e

f

g

h

i

jk

l

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 143: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 4UN04-0

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 144: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 4UN04-1

Poles of dividing cell

Mark

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2
Page 145: 04 lecture presentation

copy 2016 Pearson Education Ltd

Figure 4UN04-2

  • Slide 1
  • Introduction
  • Introduction (2)
  • Figure 40-1
  • Figure 40-2
  • Slide 6
  • 41 Microscopes reveal the world of the cell
  • 41 Microscopes reveal the world of the cell (2)
  • 41 Microscopes reveal the world of the cell (3)
  • 41 Microscopes reveal the world of the cell (4)
  • Figure 41a
  • Figure 41b
  • Figure 41c
  • Figure 41d
  • Figure 41e-0
  • Figure 41e-1
  • Figure 41e-2
  • 41 Microscopes reveal the world of the cell (5)
  • 41 Microscopes reveal the world of the cell (6)
  • 42 The small size of cells relates to the need to exchange mat
  • Figure 42a
  • 42 The small size of cells relates to the need to exchange mat (2)
  • 42 The small size of cells relates to the need to exchange mat (3)
  • Figure 42b
  • Figure 4UN01
  • 43 Prokaryotic cells are structurally simpler than eukaryotic
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (2)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (3)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (4)
  • 43 Prokaryotic cells are structurally simpler than eukaryotic (5)
  • Figure 43-0
  • Figure 43-1
  • Figure 43-2
  • 44 Eukaryotic cells are partitioned into functional compartmen
  • 44 Eukaryotic cells are partitioned into functional compartmen (2)
  • 44 Eukaryotic cells are partitioned into functional compartmen (3)
  • 44 Eukaryotic cells are partitioned into functional compartmen (4)
  • 44 Eukaryotic cells are partitioned into functional compartmen (5)
  • 44 Eukaryotic cells are partitioned into functional compartmen (6)
  • Figure 44a
  • Figure 44b
  • Slide 42
  • 45 The nucleus contains the cellrsquos genetic instructions
  • 45 The nucleus contains the cellrsquos genetic instructions (2)
  • 45 The nucleus contains the cellrsquos genetic instructions (3)
  • Figure 45
  • 46 Ribosomes make proteins for use in the cell and export
  • 46 Ribosomes make proteins for use in the cell and export (2)
  • Figure 46
  • Slide 50
  • 47 Many organelles are connected in the endomembrane system
  • 47 Many organelles are connected in the endomembrane system (2)
  • 47 Many organelles are connected in the endomembrane system (3)
  • 47 Many organelles are connected in the endomembrane system (4)
  • 48 The endoplasmic reticulum is a biosynthetic workshop
  • Figure 48a
  • Figure 48b
  • 48 The endoplasmic reticulum is a biosynthetic workshop (2)
  • 48 The endoplasmic reticulum is a biosynthetic workshop (3)
  • 49 The Golgi apparatus modifies sorts and ships cell product
  • 49 The Golgi apparatus modifies sorts and ships cell product (2)
  • Figure 49
  • 410 Lysosomes are digestive compartments within a cell
  • 410 Lysosomes are digestive compartments within a cell (2)
  • Animation Lysosome Formation
  • Figure 410a-1
  • Figure 410a-2
  • Figure 410a-3
  • Figure 410a-4
  • Figure 410b-1
  • Figure 410b-2
  • Figure 410b-3
  • 411 Vacuoles function in the general maintenance of the cell
  • Video Paramecium Vacuole
  • Figure 411a
  • Figure 411b
  • 412 A review of the structures involved in manufacturing and b
  • Figure 412
  • 412 A review of the structures involved in manufacturing and b (2)
  • Slide 80
  • 413 Mitochondria harvest chemical energy from food
  • 413 Mitochondria harvest chemical energy from food (2)
  • 413 Mitochondria harvest chemical energy from food (3)
  • Figure 413
  • 414 Chloroplasts convert solar energy to chemical energy
  • 414 Chloroplasts convert solar energy to chemical energy (2)
  • Figure 414
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve
  • 415 EVOLUTION CONNECTION Mitochondria and chloroplasts evolve (2)
  • Figure 415
  • Figure 415-1
  • Figure 415-2
  • Figure 415-3
  • Slide 94
  • 416 The cellrsquos internal skeleton helps organize its structure
  • Video Cytoplasmic Streaming
  • 416 The cellrsquos internal skeleton helps organize its structure (2)
  • 416 The cellrsquos internal skeleton helps organize its structure (3)
  • 416 The cellrsquos internal skeleton helps organize its structure (4)
  • Figure 416-0
  • Figure 416-1
  • Figure 416-2
  • Figure 416-3
  • Figure 416-4
  • Figure 416-5
  • Figure 416-6
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto
  • 417 SCIENTIFIC THINKING Scientists discovered the cytoskeleto (2)
  • Figure 417
  • 418 Cilia and flagella move when microtubules bend
  • Video Paramecium Cilia
  • Video Chlamydomonas
  • Figure 418a
  • Figure 418b
  • 418 Cilia and flagella move when microtubules bend (2)
  • 418 Cilia and flagella move when microtubules bend (3)
  • Animation Cilia and Flagella
  • Figure 418c-0
  • Figure 418c-1
  • Figure 418c-2
  • 418 Cilia and flagella move when microtubules bend (4)
  • 419 The extracellular matrix of animal cells functions in supp
  • 419 The extracellular matrix of animal cells functions in supp (2)
  • Figure 419
  • 420 Three types of cell junctions are found in animal tissues
  • Animation Desmosomes
  • Animation Gap Junctions
  • Animation Tight Junctions
  • Figure 420
  • 421 Cell walls enclose and support plant cells
  • Figure 421
  • 422 Review Eukaryotic cell structures can be grouped on the b
  • Table 4-22-0
  • Table 4-22-1
  • Table 4-22-2
  • You should now be able to
  • You should now be able to (2)
  • You should now be able to (3)
  • You should now be able to (4)
  • Table 4-1
  • Figure 4UN02
  • Figure 4UN03
  • Figure 4UN04-0
  • Figure 4UN04-1
  • Figure 4UN04-2